Publications

  1. Xingjian Yu, Ruiwu Liu, Kit S. Lam. Affinity peptides for diagnosis and treatment of viral infections. United States Patent pending, 2023.
  2. Kit S. Lam, Xingjian Yu, Kit S. Lam. Site-specific covalent ligation of human serum albumin. United States Patent pending, 2022.
  3. Yu-Jui Yvonne Wan, Kit S. Lam, Ruiwu Liu. Compositions comprising HDAC inhibitors and retinoids. United States Patent pending 2020
  4. Kit S Lam, Lu Zhang. Smart peptides and transformable nanoparticles for cancer immunotherapy. United States Patent pending.
  5. Kit S Lam, Lu Zhang, Di Jing, Lei Wang. Smart peptide-based targeting and transformable nanoparticles for cancer therapy. United States Patent pending.
  6. Aijun Wang, Dake Hao, Kit S Lam. Engineered scaffolds for vascularized tissue repair. United States Patent number 11246961, February 15, 2022.
  7. Kit S Lam, Yuanpei Li. Reversible crosslinked micelle systems. United States Patent number 11192978, December 7, 2021.
  8. Kit S Lam, Yuanpei Li, Kai Xiao, Caihong Feng. Poly(vinyl alcohol) nanocarriers. United States Patent number 11135309, October 5, 2021.
  9. Kit S Lam, Joyce Lee, Juntao Lu. Apolipoprotein nanodiscs with telodendrimer. United States Patent number 11053322, July 6, 2021.
  10. Kit S Lam, Ruiwu Liu, and Tsung-Chieh Shih. LLS compounds for treatment of cancer. United States Patent number 10844052, Nov 24, 2020.
  11. Kit S Lam, Lin Tian, Sara Ahadi, Ruiwu Liu. Functional Illumination in Living Cells. United States Patent number 10598667, March 24, 2020.
  12. Diana Lac, Chun Feng, Gaurav Bhardwaj, Siddarth Chandrasekaran, and Kit S Lam. Site-specific covalent chemical ligation to monoclonal and polyclonal immunoglobulin.United States Patent number 10,588,982 B2, March 17, 2020.
  13. Juntao Luo and Kit S. Lam. Telodendrimers with enhanced drug delivery. United States Patent number 10,406,233, September 10, 2019.
  14. Chongxian Pan, Hongyong Zhang, Kit S Lam, and Olulanu H. Aina. United States Patent number 10,335,365, July 2, 2019.
  15. Kit S. Lam, Yuanpei Li, and Chongxian Pan. United States Patent number 10,238,750, March 26, 2019.
  16. Kit S Lam, Yuanpei Li, Junto Luo, and Kai Xiao. Reversiblely crosslinked micelle systems. United States Patent number 10,106,650, May 9, 2017.
  17. Juntao Luo, Wei He, Kit S Lam, Paul Henderson, and Matt Coleman. Apolipoprotein nanodiscs with telodendrimer. United States Patent number 9644038, May 9, 2017.
  18. Kit S Lam, Yuanpei Li, Chong-Xian Pan, Tzu-yin Lin. Porphyrin modified telodendrimers. United States Patent number 9642916, May 9, 2017.
  19. Kit S. Lam and Juntao Luo. Nanocarriers for drug delivery. United States Patent number 9579400, February 28, 2017.
  20. Kit S. Lam, Ruiwu Liu, Wei Yao, and Nancy Lane. LLP2A-Bisphosphonate conjugates for osteoporosis treatment. United States Patent Number 9561256, February 7, 2017.
  21. Chong-xian Pan, Hongyong Zhang, Kit S. Lam, and Olulanu H Aina. Bladder Cancer Specific Ligand Peptides. United States Patent Number 9539340. January 10, 2017.
  22. Ekama Onofiok, Kit S. Lam, and Juntao Luo. Three-dimensional cell adhesion matrix. United States Patent number 9296988. March 29, 2016.
  23. Kit S Lam, Yan Wang, Wenwu Xiao. RGD-containing cyclic peptides. United States Patent Number 9073974. July 7, 2015.
  24. Chong-xian Pan, and Kit S. Lam. Bladder Cancer Specific Ligand Peptides. United States Patent Number 8946379. February 3, 2015.
  25. Kit S. Lam, Ruiwu Liu, Wei Yao, and Nancy Lane. LLP2A-Bisphosphonate conjugates for osteoporosis treatment. United States Patent Number 9119884, September 1, 2015.
  26. Kit S Lam, Juntao Luo, and Joyce S Lee. Telodendrimer nanodiscs without apolipoprotein. United States Patent Number 8895055. November 25, 2014.
  27. Rick Carpenter, Mirela Andrei, Ruiwu Liu, Kit S. Lam, and Mark J. Kurth. Heterocyclic ligand optimization for a4b1 integrin. United States Patent Number 8486370. July 16, 2013.
  28. Lee-way Jin, Kit S. Lam, Ruiwu Liu, Hyun-Seok Hong, Izumi Maezawa. Ab-binding small molecules. United States Patent Number 8,168,800. May 1, 2012.
  29. Carlito B Lebrilla, Hyun J An, Kit S Lam, Suzanne Miyamoto. Methods of Oligosaccharide profiling for the detection of cancer. United States Patent Number 7,651,847. January 26, 2010.
  30. Lori A Hazlehurst, William S Dalton, Anne E Cress, and Kit Lam. HYD1 peptides as anti-cancer agents. United States Patent Number 7,632,814. December 12, 2009.
  31. Kit S Lam, Ruiwu Liu, and Li Peng. Alpha-4 beta-1 integrin ligands for imaging and therapy. United States Patent Number 7,576,175. August 18, 2009.
  32. Kit S. Lam and Alan Lehman. Methods for determiing differences in molecular interactions and for screening a combinatorial library. United States Patent Number 7,291,456. November 6, 2007.
  33. Kit S. Lam and Derick Lau. Methods for screening combinatorial bead library, ligands for cancer cells. United States Patent Number 7,262,269. August 28, 2007.
  34. Derick Lau and Kit S. Lam. Methods for screening combinatorial bead library, capturing cells from body fluids, and ligands for cancer cells. United States Patent Number 6,670,142 B2 December 30, 2003.
  35. Michal Lebl and Kit S. Lam. Topologically segregated encoded solid phase libraries comprising linkers having an enzymatically susceptible bond. United States Patent Number 6,090.912. July 18, 2000.
  36. Kit S. Lam and Sydney E. Salmon. Bio-oligomer libraries and a method of use thereof. United States Patent Number 5,858,670. Jan 12, 1999.
  37. Michal Lebl, Kit S. Lam, Sydney E. Salmon, Victor Krchnak, Nikolai Sepetov, and Peter Kocis. Topologically segregated, encoded solid phase libraries. United States Patent Number 5,840,485. Nov 24, 1998.
  38. Kit S. Lam and Sydney E. Salmon. Apparatus and methods for random polymer synthesis. United States Patent Number 5,651,943. July 29, 1997.
  39. Kit S. Lam and Sydney E. Salmon. Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof. United States Patent Number 5,650,489. July 22, 1997.
  40. Michal Lebl, Viktor Krchnak, Petr Kocis and Kit S. Lam. Selectively cleavable linkers based on iminodiacetic acid esters for solid phase peptide synthesis. United States Patent Number 5,635,598. June 3, 1997.
  41. Kit S. Lam and Sydney E. Salmon. Method of screening a peptide library. United States Patent Number 5,510,240. April 23, 1996.
  42. Henry S. Kaplan, N.N.H. Teng, Kit S. Lam and F. Calvo-Riera. Methods and cell lines for immortalization and monoclonal antibody production by antigen stimulated B-lymphocytes. United States Patent Number: 4,574,116. Mar 4, 1986.
  1. Yu X, Pan B, Zhao C, Shorty D, Solano LN, Sun G, Liu R, and Lam KS. Discovery of Peptidic Ligands against the SARS-CoV‑2 Spike Protein and Their Use in the Development of a Highly Sensitive Personal Use Colorimetric COVID-19 Biosensor. ACS Sensors, 6: 2159-2168, 2023.
  2. Song H, Gao K, Hao D, Li A, Liu R, Anggito B, Yin B, Jin Q, Lam KS, Smith LR, Dartora V, Panitch A, Farmer D, Wang A. Engineered multi-functional, pro-angiogenic collagen-based scaffolds loaded with endothelial cells promote large deep burn wound healing. Frontiers in Pharmacology, 2023 Mar 1:14:1125209.
  3. Wang Y, Zhang W, Yip H, Qu C, Hu H, Chen X, Lee T, Yang X, Yang B, Kumar P, Lee SY, Casimiro J, Zhang J, Wang A, Lam KS. SIC50: Determining Drug Inhibitory Concentrations Using a Vision Transformer and an Optimized Sobel Operator. Patterns, 4(2): 10686, 2023.
  4. Xingjian Yu X, Ruan M, Wang Y, Nguyen A, Xiao W, Ajena Y, Liu R, and Lam KS. Site-Specific Albumin-selective Ligation to Human Serum Albumin under Physiological Condition. Bioconjugate Chemistry, 33(12): 2332-2340, 2022.
  5. Li Y, Zhang L, Yang P, Zhang K, Gong X, Hou D, Cao H, Wu X, Liu R, Lam KS, and Wang L. Bioinspired Screening of Anti-Adhesion Peptides against Blood Proteins for Intravenous Delivery of Nanomaterials. Nano Letters, in press, 2022.
  6. Jing D, Jiang N, Wang F, Mao C, Han S, Ho PY, Xiao W, Li Y, Li J, Zhang L, Lam KS. Nanoradiosensitizer with good tissue penetration and enhances oral cancer radiotherapeutic effect. Biomaterials. Sept 1; 289:121769, 2022.
  7. Zhu Z, Ma A, Zhang H, Lin T, Xue X, Farrukh H, Zhu S, Shi W, Yuan R, Cao Z, Sekhar VC, Chittepu R, Prabhala R, Li Y, Lam KS, and Pan C. Phototherapy with cancer-specific nanoporphyrin potentiates immunotherapy in bladder cancer. Clinical Cancer Research, Aug 3; CCR-22-1362, 2022.
  8. Zhang L, Bo R, Wu Y, Li L, Zhu Z, Ma A, Xiao W, Huang Y, Rojalin T, Yin X, Mao C, Wang F, Wang Y, Zhang H, KE Low, Lee K, Ajena Y, Jing D, Zhang D, Baehr CM, Liu R, Wang L, Li Y, and Lam KS. Programmable bispecific nano-immunoengager that captures T cells and reprograms tumor. Nano Letters, 22(17): 6866-6876, 2022. PMID: 35926215
  9. Svobodova J, Frolikova M, Ded L, Cerny J, Postlerova P, Palenikova V, Valaskova E, Machan R, Pacey A, Holubcova Z, Koubek P, Ezrov Z, Nahacka Z, Tanno A, Liu R, Clark N, Neuzil J, Ikawa M, Erickson K, Lam KS, Moore H & Komrskova K. MAIA, Fc receptor-like 3, supersedes JUNO as IZUMO1 receptor during human fertilization. Science Advances. 7 Sep 2022, Vol 8, issue 36, 2022.
  10. Hao D, Liu R, Fernandez TG, Pivetti C, Jackson JE, Kulubya ES, Jiang HJ, Ju HY, Liu WL, Panitch A, Lam KS, Leach JK, Farmer DL, Wang A. A bioactive material with dual integrin-targeting ligands regulates specific endogenous cell adhesion and promotes vascularized bone regeneration in adult and fetal bone defects. Bioact Mater. 2022 May 29; 20:179-193. doi: 10.1016/j.bioactmat.2022.05.027. eCollection 2023 Feb.PMID: 35663336
  11. Hao D, Lu L, Song H, Duan Y, Chen J, Carney R, Li JJ, Zhou P, Nolta J, Lam KS, Leach JK, Farmer DL, Panitch A, Wang A. Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair. Theranostics. 2022 Aug 8;12(13):6021-6037. doi: 10.7150/thno.70448. eCollection 2022.PMID: 35966577
  12. Bansal S, Vu K, Liu R, Ajena Y, Xiao W, Menon SM, Bennett AB, Gelli A, Lam KS. Discovery and characterization of a potent antifungal peptide through OBOC combinatorial library screening. ACS Infectious Disease, 8(7): 1291-1302, 2022.
  13. Zhou J, Meili VS, Chen EY, Kapre R, Nagalla R, Xiao W, Borowsky AD, Lam KS, Liu WF, Louie AY. Magnetic Resonance Imaging of Tumor-Associated-Macrophages (TAMs) with a Nanoparticle Contrast Agent. RSC Advances, 12: 7742-7756, 2022
  14. Jiang N, Xie B, Xiao W, Fan M, Xu S, Duan Y, Hamsafar Y, Evans A, Huang J, Zhou W, Lin X, Ye N, Wanggou S, Chen W, Jing D, Fragoso R, Dugger B, Willson P, Coleman M, Xia S, Li X, Sun L, Monjazeb A, Wang A, Murphy W, Kung H, Lam K, Chen H, and Li JJ. Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion. Nature Communication, 13: 1511, 2022.
  15. Solbach F, Bernardi A, Bansal S, Budamagunta MS, Krep L, Leonhard K, Voss JC, Lam KS, and Faller R. Determining structure and action mechanism of LBF14 by molecular simulation. J Biomol. Struct Dyn Aug 23, 1-12, 2021.
  16. Shimkunas R, Hegyi B, Jian Z, Shaw JA, Kazemi-Lari MA, Mitra D, Leach JK, Li X, Jaradeh M, Balardi N, Chen YJ, Escobar AL, Baker AJ, Bossuyt J, Banyasz T, Chiamvimonvat N, Lam KS, Bers DM, Izu LT, Chen-Izu Y. Mechanical Load Regulates Excitation-Ca2+ Signaling-Contraction in Cardiomyocyte. Circulation research, 772-774, 2021.
  17. Wang Y, Li Y, Cao J, Meng Q, Li X, Zhang Y, Lam KS, Hong A, Liu R, and Chen X. Development and Characterization of a Novel Peptide—Drug Conjugate with DM1 for Treatment of FGFR2-Positive Tumors. Biomedicines.  9: 849, 2021.
  18. He S, Walimbe T, Chen H, Gao K, Kumar P, Wei Y, Hao D, Liu R, Farmer DL, Lam KS, Zhou J, Panitch A, Wang A. Bioactive extracellular matrix scaffolds engineered with proangiogenic proteoglycan mimetics and loaded with endothelial progenitor cells promote neovascularization and diabetic wound healing. Bioactive Materials, 10: 460-473, 2021.
  19. Baehr C, Zhang L, Wu Y, Domokos A, Xiao W, Wang L, Lam KS. Transformable Amyloid-Beta Mimetic Peptide Amphiphiles for Lysosomal Disruption in Non-Small Cell Lung Cancer. Biomaterials 277: 121078, 2021.
  20. Yang P, Li Y, Cao Y, Zhang L, Wang J, Lai Z, Zhang K, Shorty D Xiao W, Cao H, Wang L, Wang H, Liu R, Lam KS.  Rapid Discovery of Self-Assembling Peptides with One-Bead One-Compound Peptide Library. Nature Communication 12:4494, 2021.
  21. Saha K , Sontheimer EJ , Brooks PJ,………Lam KS…….. The SCGE Consortium. The NIH Somatic Cell Genome Editing program. Nature April 2021.
  22. Lee A, Ijiri M, Rodriguez R, Gandour-Edwards R, Lee J, Tepper C, Li Y, Beckett L, Lam K, Goodwin N, Satake N. Novel patient metastatic pleural effusion-derived xenograft model of renal medullary carcinoma demonstrates therapeutic efficacy of Sunitinib. Frontiers in Oncology, section Molecular and Cellular Oncology. 2021.
  23. Zhang L, Wu Y, Yin X, Zhu Z, Rojalin T, Xiao W, Zhang D, Huang Y, Li L, Baehr C, Yu X, Ajena Y, Li Y, Wang L, Lam KS. Modulation of the Morphology, Phototherapeutic Properties and Pharmacokinetics of Smart Nanomaterials. ACS Nano, 15: 468-479, 2021.
  24. Wang Y, Fan H, Ji Y, Reynolds K, Gu R, Gan Q, Yamagami T, Zhao T, Hamad S, Bizen N, Takebayashi H, Chen Y, Wu S, Pleasure D, Lam K, Zhou CJ. Olig2 regulates terminal differentiation and maturation of peripheral olfactory sensory neurons. Cell Mol Life Sci. 77(18): 3597-3609, 2020.
  25. Xiao K, Liu Q, Suby N, Xiao W, Agrawal R, Vu M, Zhang H, Luo Y, Li Y, and Lam KS. LHRH-targeted redox-responsive crosslinked micelles impart selective drug delivery and effective chemotherapy in triple-negative breast cancer. Advanced Healthcare Materials. In press, 2020
  26. Dehghani T, Thai PN, Sodhi H, Ren L, Sirish P, Nader CE, Timofeyev V, Overton JL, Li X, Lam KS, Chiamvimonvat N, Panitch A. Selectin-Targeting Glycosaminoglycan-Peptide Conjugate Limits Neutrophil Mediated Cardiac Reperfusion Injury. Cardiovasclar Research, in press, 2020.
  27. Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, Sweeney C, Shen R, Lin TY, Pan CX, Ozpiskin OM, Woloschak G, Grdina DJ, Vaughan AT, Wang JM, Xia S, Monjazeb AM, Murphy WJ, Sun LQ, Chen HW, Lam KS, Weichselbaum RR, Li JJ. Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells . Nature Communication, 11: 4591, 2020. PMID: 32929084
  28. Shivani B, Su WC, Budamagunta M, Xiao W, Ajena Y, Liu R, Voss JC, Carney RP, Parikh AN, Lam KS. Discovery and mechanistic characterization of a structurally-unique membrane active peptide. BBA- Biomembranes, 1862 (10): 183394, 2020.
  29. Hao D, Swindell HS, Ramasubramanian L, Liu R, Lam KS, Farmer DL, Wang AJ. Extracellular matrix mimicking nanofibrous scaffolds modified with mesenchymal stem cell-derived extracellular vesicles for improved vascularization. Frontiers Bioengineering, in press, 2020.
  30. Jiang M, Liu L, Liu R, Lam KS, Land NE, Yaio W. A new anabolic compound, LLP2A-Ale, reserves periodontal bone loss in mice through augmentation of bone formation. BMC Pharmacol Toxicol. 21: 76, 2020.
  31. Silva A, XiaoW, Wang Y, Wang W, Chang HW, Ames JB, Lam KS, Zhang Y. Structure-activity relationship of RGD-containing cyclic octapeptide and avb3 integrin allows for rapid identification of a new peptide antagonist. Int J Mol Sci. 21(9):3026, 2020. PMID:32249271.
  32. Hao D, Liu R, Gao K, He C, He S, Zhao C, Sun G, Farmer DL, Panitch A, Lam KS, Wang A. Developing an injectable nanofibrous extracellular matrix hydrogel with an integrin avb3 ligand to improve endothelial cell survival, engraftment and vascularization. Front Bioeng Biotechnol. 8:890, 2020.
  33. Hao D, Fan Y, Xiao W, Liu R, Pivetti C, Walimbe T, Guo F, Zhang X, Farmer DL, Wang F, Panitch A, Lam KS, Wang A. Rapid endothelialization of small diameter vascular grafts by a bioactive integrin-binding ligand specifically targeting endothelial progenitor cells and endothelial cells. Acta Biomaterial. 108: 178-193, 2020.
  34. Wu H, Lu H, Xiao W, Yang J, Du H, Shen Y, Qu H, Jia B, Manna SK, Ramachandran M, Xue X, Ma Z, Xu X, Wang Z, He Y, Lam KS, Zawadzki RJ, Li Y, and Lin TY. Sequential targeting in crosslinking nanotheranostics for tracking the multibarriers of brain tumors. Adv Mater. 19 Feb 2020, 32(14):e1903759.
  35. Cong Z, Zhang L, Ma SQ, Lam KS, Yang FF, Liao YH. Size-transformable hyaluronan stacked self-assembling peptide nanoparticles for improved transcellular tumor penetration and photo-chemo combination therapy. ACS Nano 14:1958-1970, 2020.
  36. Wang Z, Xue X, Lu H, He Y, Lu Z, Chen Z, Yuan Y, Tang N, Dreyer CA, Quigley L, Curro N, Lam KS, Walton JH, Lin TY, Louie AY, Gilbert DA, Liu K, Ferrara KW, and Li Y. Two-way magnetic resonance tuning and enhanced subtraction imaging for non-invasive and quantitative biological imaging. Nature Nanotechnology, 15(6):482-490, 2020.
  37. Hao D, Ma B, He C, Liu R, Farmer DL, Lam KS, Wang A. Surface modification of polymeric electrospun scaffolds via a potent and high-affinity integrin α4β1 ligand improved adhesion, spreading and survival of human chorionic villus-derived mesenchymal stem cells: a new sight for fetal tissue engineering. Journal of Materials Chemistry B, 8: 1649-1659, 2020.
  38. Zhang L, Jing L, Jiang N, Rojalin T, Baehr CM, Zhang D, XiaoW, Wu Y, Cong Z, Li J, Li Y, Wang L, and Lam KS. Transformable peptide nanoparticles arrest HER2 signalling and cause cancer cell death in vivo. Nature Nanotechnology, 15:145-153, 2020.
  39. Zhang L, Huang Y, Lindstrom AR, Lin TY, Lam KS, and Li Y. Peptide-based materials for cancer immunotherapy. Theranostic, 9(25):7807-7825 (2019). PMID:31695802
  40. Marusina AI, Merleev AA, Luna JI, Olney L, Haigh NE, Yoon D, Guo C, Ovadia EM, Shimoda M, Luxardi G, Boddu S, Lal NN, Takada Y, Lam KS, Liu R, Isseroff RR, Le S, Nolta JA, Kloxin AM, Maverakis E. Tunable hydrogels for mesenchymal stem cell delivery: integrin-induced transcriptome alterations and hydrogel optimization for human wound healing. Stem Cells. 2019 Oct 24. 2019. PMID: 31648388
  41. Yang F, Xiao W, Liu Y, Liu R, Kramer R, Li X, Ajena Y, Baehr CM, Rojalin T, Zhang H, Lam KS. One-bead one-compound combinatorial library derived targeting ligands for detection and treatment of oral squamous cancer. Oncotarget. 2019 10(52):5468-5479. PMID 31534631.
  42. Cai D, Wang J, Gao B, Li J, Wu F, Zou J, Xu J, Jiang Y, Zou H, Huang Z, Borowsky A, Bold R, Lara P, Li JJ, Chen X, Lam K, To K, Kung HJ, Fiehn O, Zhao R, Evans R, and Chen H. RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. Nature Communication. 10: 4621, 2019. PMID: 31604910.
  43. Xiao W, Ma W, Wei S, Li Q, Liu R, Carney RP, Yang K, Lee J, Nyugen A, Yoneda KY, Lam KS, Li T. High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer. J of Hematology and Oncology, 12: 56, 2019. PMID:31182116.
  44. Shih TC, Fan Y, Kiss S, Li X, Deng XN, Liu R, Chen XJ, Carney R, Chen A, Ghosh PM, Lam KS. Galectin-1 Inhibition Induces Cell Apoptosis Through Dual Suppression of CXCR4 and Ras Pathways in Human Malignant Peripheral Nerve Sheath Tumors. Neuro-Oncology, 21:1389-1400, 2019. PMID: 31127849.
  45. Wen H, Xiao W, Biswas S, Cong ZQ, Liu XM, Lam KS, Liao YH, Deng W. Alginate Hydrogel Modified with a Ligand Interacting with α3β1 Integrin Receptor Promotes the Differentiation of 3D Neural Spheroids toward Oligodendrocytes in Vitro. ACS Appl Mater Interfaces. 2019 Feb 13;11(6):5821-5833. PMID: 30645095.
  46. Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen S, Lam KS, To KF, Kung HJ, Fiehn O, Zhao R, Evans RM, Chen HW. ROR-g is a targetable master regulator of cholesterol biosynthesis in a caner subtype. Nature Communiation. 10:4621, 2019. PMID: 31604910
  47. Kumar P, Becker JC, Gao K, Carney RP, Lankford L, Keller BA, Herout K, Lam KS, Farmer DL, Wang A. Neuroprotective effect of placenta-derived mesenchymal stromal cells: role of exosomes. FASEB J. 2019 May; 33(5):5836-5849. PMID: 30753093
  48. Lam KS. Affinity Selection and sequencing. Nat Chem Biol. 2019 Apr;15(4):320-321. doi: 10.1038/s41589-019-0253-2. PMID :30886435
  49. Xie B, Zhang L, Hu W, Fan M, Jiang N, Duan Y, Jing D, Xiao W, Fragoso RC, Lam KS, Sun LQ, Li JJ. Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cells. Redox Biol. 2019 Apr 9, 24:101189. doi: 10.1016/j.redox.2019.101189. [Epub ahead of print] PMID: 30986607
  50. Lin TY, Zhu Y, Li Y, Zhang H, Ma AH, Long Q, Keck J, Lam KS, Pan CX, Jonas BA. Daunorubicin-containing CLL1-targeting nanomicelles have anti-leukemia stem cell activity in acute myeloid leukemia. Nanomedicine. 2019 August. pii: S1549-9634(19)30088-7. PMID: 31055076
  51. Jafari S, Thillier Y, Ajena YH, Shorty D, Li J, Huynh JS, Pan BM, Pan T, Lam KS, Liu R. Rapid discovery of Illuminating peptides for instant detection of opioids in blood and body fluids. Molecules. May 10. 24 (2019). PMID: 31083395
  52. Ngo T, Corrales A, Bourne T, Elmojahid S, Lam KS, Diaz E. Alternative splicing of MXD3 and its regulation of MXD3 levels in glioblastoma. Frontiers in Molecular Biosciences, Feb 19; 6:5, 2019. PMID: 30838212.
  53. Li J, Zhao S, Yang G, Liu R, Xiao W, Disano P, Lam KS, Pan T. Combinatorial Peptide Microarray Synthesis Based on Microfluidic Impact Printing. ACS Comb Sci. 21: 6-10, 2019
  54. Wang Z, Xue X, He Y, Lu Z, Jia B, Wu H, Yuan Y, Huang Y, Wang H, Lu H, Lam KS, Lin TY, Li Y. Novel redox-responsive polymeric magnetosomes with tunable magnetic resonance property for in vivo drug release visualization and dual-modal cancer therapy. Adv Funct mater 2018 August 15. PMID:31303869.
  55. Goswami M, Wang X, Zhang P, Xiao W, Karlen SJ, Li Y, Zawadzki RJ, Burns ME, Lam KS, Pugh EN Jr. Novel window for cancer nanotheranostics: non-invasive ocular assessments of tumor growth and nanotherapeutic treatment efficacy in vivo. Biomed Opt Express. 2018 Dec 11;10(1):151-166. PMID: 30775090
  56. Zhang L, Jing D, Wang L, Sun Y, Li JJ, Hill B, Yang F, Li Y, Lam KS. Unique Photochemo-Immuno-Nanoplatform against Orthotopic Xenograft Oral Cancer and Metastatic Syngeneic Breast Cancer. Nano Lett. 2018 Nov 14; 18(11):7092-7103.
  57. Li J, Tan W, Xiao W, Carney RP, Men Y, Li Y, Quon G, Ajena Y, Lam KS, Pan T. A Plug-and-Play, Drug-on-Pillar Platform for Combination Drug Screening Implemented by Microfluidic Adaptive Printing. Anal Chem. 90: 13969-13977, 2018.
  58. Arun A, Tepper C, and Lam KS. Identification of integrin drug targets for 17 solid tumor types. Oncotarget, 9 (53): 30146-30162, 2018.
  59. Shih TC, Liu R, Wu CT, Li X, Xiao W, Deng X, Kiss Z, Wang T, Chen X, Carney RP, Kung HJ, Duan Y, Ghosh PM, Lam KS. Targeting galectin-1 impairs castration-resistant prostate cancer progression and invasion. Clinical Cancer Research, 24: 4319-4331, 2018.
  60. Xiao K, Liu Q, Al Awwad N, Zhang H, Lai L, Luo Y, Lee JS, Li Y, Lam KS. Reversily disulfide cross-linked micelles improve the pharmacokinetics and facilitate the targeted on-demand delivery of doxorubicin in the treatment of B-cell lymphoma. Nanoscale. 10 (17): 8207-8216, 2018.
  61. Wang XS, Zhang L, Li X, Kong DJ, Hu XC, Ding XZ, Yang JQ, Zhao MQ, He Y, Lam KS, Gao SG, Lin TY, Li Y. Nanoformulated paclitaxel and AZD9291 synergistically eradicate non-small-cell lung cancers in vivo. Nanomedicine (Lond) 13: 1107-1120, 2018.
  62. Long Q, Lin TY, Huang Y, Li X, Ma AH, Zhang H, Carney R, Airhart S, Lam KS, deVere White RW, Pan CX, Li Y. Image-guided photo-therapeutic nanoporphyrin synergized HSP90 inhibitor in patient-derived xenograft bladder cancer model. Nanomedicine. 14:789-799, 2018.
  63. Yamagami T, Pleasure DE, Lam KS, Zhou CJ. Transient activation of Wnt/β-catenin signaling reporter in fibrotic scar formaiton after compression spinal cord injury in adult mice. Biochem Biophys Res Commun. 496 (4): 1302-1307, 2018.
  64. Li J, Carney RP, Liu R, Fan J, Zhao S, Chen Y, Lam KS, Pan T. Microfluidic print-to-synthesis platform for efficient preparation and screening of combinatorial peptide microarrays. Analytical Chemistry, 90:5833-5840, 2018.
  65. Zhang L, Yin T, Li B, Zheng R, Qiu C, Lam KS, Zhang Q, Shuai X. Size-modulable nanoprobe for high-performance ultrasound imaging and drug delivery against cancer. ACS Nano, 12(4):3449-3460, 2018.
  66. Xiao W, Suby N, Xiao K, Lin TY, Al Awwad N, Lam KS, Li Y. Extremely long tumor retention, multi-responsive boronate crosslinked micelles with superior therapeutic efficacy for ovarian cancer. Journal of Controlled Release, 264:169-179, 2017.
  67. Lee C, Carney R, Lam KS, Chan J. SERS analysis of selectively captured exosomes using an integrin-specific peptide ligand. J of Raman Spectroscopy, in press, 2017.
  68. Luo Y, Wu H, Feng C, Xiao K, Yang X, Liu Q, Lin T-y, Zhang H, Wsalton JH, Ajena Y, Hu Y, Lam KS, and Li Y. “One-Pot” fabrication of highly versatile and biocompatible poly(vinyl alcohol)-porphyrin-based nanotheranostics. Theranostics. 7:3901-3914, 2017.
  69. Yang X, Xue X, Luo Y, Lin TY, Zhang H, Lac D, Xiao K, He Y, Jia B, Lam KS, Li Y. Sub-100nm, long tumor retention SN-38-loaded photonic micelles for tri-modal cancer therapy. J Controlled Release 261:297-306, 2017.
  70. He W, Felderman M, Evans AC, Geng J, Homan D, Bourguet F, Fischer NO, Li Y, Lam KS, Noy A, Xing L, Cheng RH, Rasley A, Blanchette CD, Kamrud K, Wang N, Gouvis H, Peterson TC, Hubby B, Coleman MA. Cell-free production of a functional oligomeric form of a chlamydia major outer membrane protein (MOMP) for vaccine development. J Biol Chem. July 24, 2017.
  71. Wang XS, Kong DJ, Lin TY, Izumiya Y, Ding XZ, Zhang L, Hu XC, Yang JQ, Gao SG, Lam KS, and Li YP. A versatile nanoplatform for synergistic combination therapy to treat human esophageal cancer. Acta Pharmacol Sin. 38(6): 931-942, 2017.
  72. Xiao K, Lin T, Lam KS, and Li YP. A facile strategy for fine-tuning the stability and drug release of stimuli-responsive cross-linked micellar nanoparticles towards precision drug delivery. Nanoscale, in press, 2017.
  73. Tang Y, Thillier Y, Liu R, Li X, Lam KS, Gao T. Single-bead quantification of peptide loading distribution for One-Bead One-Compound library synthesis using confocal Raman spectroscopy. Analytical Chemistry, in press, 2017.
  74. Carney RP, Thillier Y, Kiss Z, Sahabi A, Heleno Campos JC, Knudson A, Liu R, Olivos D, Saunders M, Tian L, Lam KS. Combinatorial library screening with liposomes for discovery of membrane active peptides. ACS Comb Sci. 19(5): 299-307, 2017.
  75. Jian C, Tu MJ, Ho PY, Duan Z, Zhang Q, Qiu JX, deVere White RW, Wun T, Lara PN, Lam KS, Yu AX, Yu AM. Co-targeting of DNA, RNA, and protein molecules provides optimal outcomes for treating osteosarcoma and pulmonary metastasis in spontaneous and experimental metastasis mouse models. Oncotarget. 8(19):30742-30755, 2017.
  76. Shih TC, Liu R., Fung G, Bhardwaj G, Ghosh PM, Lam KS. A novel galectin-1 inhibitor discovered through one-bead-two-compounds library potentiates the anti-tumor effects of paclitaxel in vivo. Mol Cancer Ther, in press, 2017.
  77. Bustos-Villalobos I, Bergstrom JW, Haigh NE, Luna JI, Marusina AI, Merleev AA, Wang EA, Sukhov A, Sultani H, Liu R, Bhardwaj G, Guo W, Kung HJ, Lam KS, W, Maverakis E. ITK inhibition for the targeted treatment of CTCL. J Dermatol Sci. Apr 3, 2017.
  78. Liu R, Li X, Lam KS. Combinatorial chemistry in drug discovery. Curr Opin Chem Biol 38:117-126, 2017.
  79. Mori S, Hatori N, Kawaguchi N, Hamada Y, Shih TC, Wu CY, Lam KS, Matsuura N, Yamamoto H, Takada YK, Takada Y. The integrin-binding defective FGF2 mutants potently suppress FGF2 signaling and angiogenesis. Bioscience Reports, in press, 2017.
  80. Bharadwaj G, Nhan V, Yang S, LiX, Narayanan A, Macarenco AC, Shi Y, Yang D, Vieira LS, Xiao W, Li Y, Lam KS. Cholic Acid Based Novel Micellar Nano-platform for Delivering FDA Approved Taxanes. Nanomedicine 12(10):1153-1164, 2017.
  81. Carney R, Hazari S, Colquhoun M, Tran D, Hwang B, Mulligan M, Bryers J, Girda E, Leiserowitz G, Smith Z, Lam KS. Multispectral optical tweezers for biochemical fingerprinting of CD9-positive exosome subpopulations. Analytical Chemistry, in press, 2017.
  82. Carney R, Hazari H, Rojalin T, Knudson A, Gao T, Tang Y, Liu R, Viitala T, Yliperttula M, and Lam K S. Targeting Tumor-Associated Exosomes with Integrin-Binding Peptides. Advanced Biosystems, in press, 2017.
  83. Hao D, Xiao W, Liu R, Kumar P, Li Y, Zhou P, Guo F, Farmer DL, Lam KS, Wang F, Wang A. Discovery and Characterization of a Potent and Specific Peptide Ligand Targeting Endothelial Progenitor Cells and Endothelial Cells for Tissue Regeneration. ACS Chem, 12(4):1075-1086, 2017.
  84. Orbay H, Li Y, Xiao W, Cherry SR, Lam K, Sahar DE. Developing a Nanoparticle-Delivered High-Efficacy Treatment for Infantile Hemangiomas Using a Mouse Hemangioendothelioma Model. Plast Reconstr Surg, 138:410-7, 2016.
  85. Yao W, Lay Y, Kot A, Liu R, Zhang H, Chen H, Lam K, and Lane N. Improved mobilization of exogenous mesenchymal stem cells to bone for fracture healing and sex difference. Stem Cells. 34: 2587-2600, 2016.
  86. Pan A, Zhang H, Li Y, Lin TY, Wang F, Lee J, Cheng M, Dall’Era M, Li T, deVere White R, Pan CX, Lam KS. Disulfide-crosslinked nanomicelles confer cancer-specific drug delivery and improve efficacy of paclitaxel in bladder cancer. Nanotechnology. 27(42): 425103, 2016.
  87. Lin TY, Li Y, Liu Q, Chen JL, Zhang H, Lac D, Zhang H, Ferrara KW, Wachsmann, Hogiu S, Li T, Airhart S, deVere White R, Lam KS, Pan C. Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer. Biomaterials 104-339-351, 2016.
  88. Lin TY, Guo W, Long Q, Ma A, Liu Q, Zhang H, Huang Y, Chandrasekaran S, Pan C, Lam KS, and Li Y. HSP90 inhibitor encapsulated photo-theranostic nanoparticles for synergistic combination cancer therapy. Theranostics. 6:1324-1335 (2016).
  89. Chen CC, Xing L, Stark M, Ou T, Holla P, Xiao K, Kamita SG, Hammock BD, Lam K, Cheng RH. Chemically activatable viral capsid functionalized for cancer targeting. Nanomedicine (London) 11:377-390 (2016).
  90. Liu R, Li X, Xiao W and Lam KS. Tumor-targeting peptides from combinatorial libraries. Adv Drug Deliv Rev. 2016 PMID: 27210583
  91. Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Zu J, Kung HJ, Evans RM, Xu Y, Chen HW. ROR-g drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nature Medicine. March 2016.
  92. Wu C, Wang DH, Wang X, Dixon S, Meng L, Ahadi S, Enter D, Chen CY, Kato J, Leon L, Ramirez L, Maeda Y, Reis C, Ribeiro B, Weems B, Kung HJ, Lam, KS. Rapid Discovery of Functional Small Molecule Ligands against Proteomic Targets through Library-Against-Library Screening. ACS Combinatorial Sciences 18:320-329, 2016. PMID:27053324
  93. Xiao W, Li T, Bononi FC, Lac D, Kekessie IA, Liu Y, Sanchez E, Mazloom A, Ma AH, Lin J, Tran J, Yang K, Lam KS, Liu R. Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of α3 integrin-expressing human tumors. EJNMMI Res. 6: 18, 2016. PMID: 26922417.
  94. Lac D, Feng C, Bhardwah G, Le H, Tran J, Xing L, Fung G, Liu R, Cheng H, Lam KS. Covalent chemical ligation strategy for mono- and polyclonal immunoglobulins at their nucleotide binding sites. Bioconjugate chemistry 2015. PMID: 26630124.
  95. Awasthi S, Izu L, Mao Z, Jian Z, Landas T, Lerner A, Shimkunas R, Woldeyesus RA, Bossuyt J, Wood BM, Chen YJ, Matthews DL, Lieu DK, Chiamvimonvat N, Lam KS, Chen-Izu Y, Chan JW. Multimodal SHG-2PF imaging of microdomain Ca2+-contraction coupling in live cardiac myocytes. Circ Res 2015. PMID: 26643875
  96. Wang Y, Xiao W, Zhang Y, Meza L, Tseng H, Takada Y, Ames JB and Lam KS. Optimization of RGD containing cyclic peptides against αvβ3 integrin. Mol Cancer Therapeutics, Dec 30, 2015. PMID: 26719578
  97. Smith ZJ, Lee C, Rojalin T, Carney RP, Hazari S, Knudson A, Lam K, Saari H, Ibanez EL, Vitala T, Laaksonen T, Yliperttula M, and Wachsmann-Hogiu S. Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane content. Journal of Extracellular Vesicles. In press Nov 2015
  98. Zhang P, Zam A, Jian Y, Wang X, Ki Y, Lam KS, Burns ME, Sarunic MV, Pugh EN and Zawadzki RJ. In vivo wide-field multispectral SLO-OCT mouse retinal imager: longitudinal imaging of ganglion cells, microglia and Müller glia, and mapping of the mouse retinal and choroidal vasculature, Journal of Biomedical Optics. 20: 126005, 2015. PMID 26677070
  99. Leung NY, Wai CY, Ho MH, Liu R, Lam KS, Wang JJ, Shu SA, Chu KH, Leung PS. Screening and identification of mimotopes of the major shrimp allergen tropomyosin using one-bead-one-compound peptide libraries. Cell Mol Immunol. 2015 Sep 14. doi: 10.1038/cmi.2015.83. PMID 26364917
  100. Ding Y, Li J, Xiao W, Xiao K, Lee JS, Bhardwaj U, Zhu Z, Digiglio P, Yang G, Lam KS, Pan T. Microfluidic-Enabled Print-to-Screen (P2S) Platform for High-Throughput Screening of Combinatorial Chemotherapy. Anal Chem. 87: 10166-71, 2015. PMID 26334956.
  101. Barisone GA, Satake N, Lewis C, Duong C, Chen C, Lam KS, Nolta J, Diaz E. Loss of MXD3 induces apoptosis of Reh human precursor B acute lymphoblastic leukemia cells. Blood Cells Mol Dis. 54(4):329-35, 2015. PMID: 25554682.
  102. Xiao K, Li YP, Wang C, Ahmad S, Vu M, Kuma K, Cheng YQ, Lam KS. Disulfide cross-linked micelles of novel HDAC inhibitor thailandepsin A for the treatment of breast cancer. Biomaterials. 67:183-93, 2015. PMID: 26218744.
  103. Liu R, Shih TC, Deng X, Anwar L, Ahadi S, Kumaresan P, Lam KS. Design, synthesis, and application of OB2C combinatorial peptide and peptidomimetic libraries. Methods Mol Biol. 1248:3-22, 2015.
  104. Wang WP, Ho PY, Chen QX, Addepalli B, Limbach PA, Li MM, Wu WJ, Jilek JL, Qiu JX, Zhang HJ, Li T, Wun T, White RD, Lam KS, Yu AM. Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional Characterization. J Pharmacol Exp Ther. 354(2):131-41, 2015.
  105. Lee C, Carney RP, Hazari S, Smith Z, Knudson A, Robetson C, Lam KS, Wachsmann-Hogiu S. 3D plasmonic nanobowl platform for the study of exosomes in solution. Nanoscale, 7: 9290-9297, 2015. (PMID: 25939587).
  106. Fujita M, Zhu K, Fujita CK, Zhao M, Lam KS, Kurth MJ, Takada YK, and Takada Y. Proinflammatory sPLA-IIA induces integrin activation through direct binding to a newly identified binding-site (site 2) in integrins α4β1, and α5β1. J Biol Chem 290: 259-71, 2014. (PMID 25398877).
  107. Guo W, Liu R, Bhardwaj G, Yang J, Changou C, Ma AH, Mazloom A, Chintapalli S, Xiao K, Xiao W, Pappanaicken K, Sanzhez E, Yeh CT, Evans C, Patterson R, Lam K., Kung HJ. Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor. Cell Death and Disease, in press, 2014.
  108. Ngo T, Barisone GA, Lam KS, Diaz E. MXD3 regulation of DAOY cell profileration dictated by time course of activation. BMC Cell Bio. 15: 30 (July 23 2014). (PMID 25053245)
  109. Li Y, Lin T, Luo Y, Liu Q, Xiao W, Guo W, Lac D, Zhang H, Feng C, Wachsmann-Hogiu S, Walton JH, Cherry SR, Rowland DJ, Kukis D, Pan C, and Lam KS. A Smart and Super Versatile "All-in-One" Theranostic Nanomedicine Platform. Nature Communication, 5: 4712, 2014. (PMID 25158161)
  110. Shi C, Yuan D, Nangia S, Xu G, Lam K, Luo J. A Structure-Property Relationship Study of the Well-defined Telodendrimers to improve hemocompatibility of nanocarriers for anticancer drug delivery. Langmuir, 30: 6878-6888, 2014. (PMID 24849780)
  111. Zhang H, Li Y, Lin TY, Xiao K, Haddad AS, Henderson PT, Jonas BA, Chen M, Xiao W, Liu R, Lam KS, and Pan CX. Nanomicelle formulation modified the pharmacokinetic profiles and cardiac toxicity of daunorubicin. Nanomedicine (Lond). 2014 Mar 17. (PMID 24628688).
  112. Jian Z, Han H, Zhang T, Puglisi JH, Izu L, Shaw JA, Onofiol E, Erickson JR, Chen Y, Horvath B, Shimkunas R, Xiao W, Li Y, Pan T, Chan J, Banyasz T, Tardiff J, Chiamvimonvat N, Bers DM, Lam KS, Chen-Izu C. Mechanochemotransduction during cardiomyocyte contraction is mediated by localized nitric oxide signaling. Science Signaling 317 (PMID 24643800)
  113. Garland SP, Wang RY, Raghunathan VK, Lam KS, Murphy CJ, Russell P, Sun G, Pan T. Photopatternable and photoactive hydrogel for on-demand generation of hydrogen peroxide in cell culture. Biomaterials. 35: 1762-1770. (PMID: 24290809)
  114. Li Y, Xiao K, Zhu W, Deng W, Lam KS. Stimuli-response cross-linked micelles for on-demand dr7g delivery against cancers. Adv Drug Deliv Rev. 66c: 58-73, 2014. (PMID 24060922).
  115. Hua S, Saunders M, Dimapasoc L, Jeong SH, Kim S, So M, Lee KS, Jae H, Lam KS, Lebrilla C, An HJ. Differentiation of cancer cell origin and molecular subtype by plasma membrane N-glycan profiling. Journal of Proteome Research, 13: 961-968, 2014. (PMID 24303873)
  116. Sun YS, Luo J, Lam KS, Zhu XD. Detection of formation and disintegration of micelles by oblique-incidence reflectivity difference microscopy. Instrument Science and Technology. 41: 545-555, 2013.
  117. Xiao K, Suby N, Li Y, and Lam KS. Telodendrimer-based nanocarriers for the treatment of ovarian cancer. Therapeutic Delivery. In press, October 2013.
  118. Kenyon NJ, Bratt JM, Lee J, Luo J, Franzi LM, Zeki AA, and Lam KS. Self-assembling nanoparticles containing dexamethasone as a novel therapy in allergic airway inflammation. PLOS ONE, in press, 2013.
  119. Jialal I, Devaraj S, Smith G, Lam K, Kumaresan P. A novel peptide inhibitor attenuates C-reactive protein’s pro-inflammatory effects in vivo. International Journal of Cardiology, in press, 2013.
  120. Guo W, Liu R, Bhardwaj G, Ma A, Changou C, Yang JC, Li Y, Feng C, Luo Y, Mazloom A, Sanchez E, Wang Y, Huang W, Patterson R, Evans CP, Lam KS, Kung H. CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostrate cancer cells and overcomes resistance to Src inhibitors. PLOS ONE, in press, 2013.
  121. Yao W, Guan M, Jia J, Dai W, Lay YE, Amugongo S, Liu R, Olivos D, Saunders M, Lam KS, Nolta J, Olvera D, Ritchie RO, and Lane NE. Reversing bone loss by directing mesenchymal stem cells to the bone. Stem Cells. In press, 2013.
  122. He W, Luo J, Bourguet F, Xing L, Yi SK, Gao T, Blanchetter C, Henderson PT, Kuhn E, Malfatti M, Murphy WJ, Cheng RH, Lam KS, Coleman MA. Controlling the diameter, monodispersity, and solubility of ApoA1 nanolipoprotein particles using telodendrimer chemistry. Protein Sci. 2013.
  123. Huang W, Shi C, Shao Y, Lam KS, and Luo J. The core-inversible micelles for hydrophilic drug delivery. Chem Commun (Camb), 49: 6674-6676, 2013.
  124. Ding Y, Huang E, Lam KS, and Pan T. Microfluidic impact printer with interchangeable cartridges for versatile non-contact multiplexed micropatterning. Lab Chip, 13: 1902-1910, 2013.
  125. Xiao W, Bononi FC, Townsend J, Li Y, Liu R, Lam KS. Immobilized OBOC combinatorial bead array to facilitate multiplicative screening. Comb Chem High Throughput Screen. 16: 441-448, 2013.
  126. Malekan H, Fung G, Thon V, Khedri Z, Yu H, Qu J, Li Y, Ding L, Lam KS, Chen X. One-pot multi-enzyme (OPME) chemoenzymatic synthesis of sialyl-Tn-MUC1 and sialyl-T-MUC1 glycopeptides containing natural or non-natural sialic acid. Bioorganic and Medicinal Chemistry. 2013.
  127. Leung PS, Wang J, Naiyanetr P, Kenny TP, Lam KS, Kurth MJ, and Gershwin ME. Environment and primary biliary cirrhosis: electrophilic drugs and the induction of AMA. J Autoimmun. 41: 79-86, 2013.
  128. Kumaresan P, Devaraj S, Huang W, Lau E, Liu R, Lam KS, and Jialal I. Synthesis and Characterization of a Novel Inhibitor of CRP-mediated Pro-Inflammatory Effects. Metabolic Syndrome and Related Disorders. 11: 177-184, 2013.
  129. Yang F, Liu R, Kramer R, Xiao W, Jordan R, Lam KS. Discovery of specific ligands for oral squamous carcinoma to develop anti-cancer drug loaded precise targeting nanotherapeutics. J Calif Dent Assoc, 40: 939-943, 2013.
  130. Ye L, Dickerson T, Kaur H, Takada YK, Fujita M, Liu R, Knapp JM, Lam KS, Schore NE, Kurth MJ, Takada Y. Identificaiton of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3. Bioorganic & Medicinal Chemistry Letters. 23: 350-345, 2012.
  131. Duru N, FanM, Candas D, Menaa C, Liu HC, Nantajit D, Wen Y, Xiao K, Eldridge A,Chromy BA, Li S, Spitz DR, Lam KS, Wicha MS, Li JJ. HER2-Associated Radioresistance of Breast Cancer Stem Cells Isolated from HER2-Negative Breast Cancer Cells. Clin Cancer Res. 18:6634-6647, 2012.
  132. Li YP, Budamagunta M, Luo J, Xiao W, Voss J, and Lam KS. Probing of the Assembly Structure and Dynamics within Nanoparticles during Interaction with Blood Proteins. ACS Nano, 6:9485-9489, 2012.
  133. Lee J, and Lam KS. Perspectives on Clinical Translation of Smart Nanotherapeutics. Therapeutic Delivery: Special issue on "Intelligent Drug Design" 3: 1359-1362, 2012.
  134. Lin T, Li Y, Zhang H, Luo J, Good win N, Gao T, deVere White R, Lam KS, Pan CX. Tumor-targeting multifunctional micelles for imaging and chemotherapy of advanced bladder cancer. Nanomedicine, 2012, in press.
  135. Wu M, Piccini M, Koh CY, Lam KS, Singh AK. Single cell microRNA analysis using microfluidic flow cytometry. PLOS One, 2012, in press.
  136. Leung PS, Lam K, Kurth MJ, Coppel RL, Gerhswin ME. Xenobiotics and autoimmunity: does acetaminophen cause primary biliary cirrhosis? Trends Mol Med. 18: 577-582, 2012.
  137. Guo W, Liu R, Ono Y, Ma AH, Martinez A, Sanchez E, Wang Y, Huang W, Mazloom A, Li J, Ning J, Maverakis E, Lam KS, Kung HJ. Molecular characteristics of CTA056, a novel Itk inhibitor which selectively targets malignant T cells and modulates oncomirs. Mol Pharmacol. 82: 938-47, 2012 (PMID: 228998868).
  138. Shaheen F, Rizvi TS, Musharraf SG, Ganesan A, Xiao K, Townsend JB, Lam KS, Choudhary MI. Solid-phase total synthesis of cherimolacyclopeptide E and discovery of more potent analogues by alanine screening. J Nat Prod. Nov 13, 2012.
  139. Lin TY, Zhang H, Luo J, LiY, Gao T, Lara PN Jr, deVere White R, Lam KS, Pan CX. Multifunctional targeting micelle nanocarriers with both imaging and therapeutic potential for bladder cancer. Int J Nanomedicine. 7:2793-2804, 2012.
  140. Hu X, Kheirolomoom A, Mahakian LM, Beegle JR, Kruse DE, Lam KS, Ferrara KW. Insonation of targeted microbubbles produces regions of reduced blood flow within tumor vasculature. Invest Radiol. 47: 398-405, 2012.
  141. Kato J, Li Y, Xiao K, Lee J, Luo J, Tuscano J, O’Donnell R, Lam KS. Disulfide cross-linked micelles for the targeted delivery of vincristine to B-cell lymphoma. Molecular Pharmaceutics. 9: 1727-1735, 2012. (PMID: 22530955)
  142. Zwingenberger AL, Kent MS, Liu R, Kukis DL, Wisner ER, DeNardo SJ, Taylor SL, and Lam KS. In vivo biodistribution and safety of 99mTc-LLP2A-Hynic in canine non-Hodgkin’s lymphoma. PLos One, 7(4):e34404, 2012.
  143. Zwingenberger AL, Kent MS, Shi C, Taylor SL, Chen X, and Lam KS. Affinity of the alpha4-beta1 integrin-targeting peptide LLP2A to canine lymphoma. Veterinary Immunology and Immunopathology. 145: 298-304, 2012. (PMDI: 22177114)
  144. Xiao K, Li Y, Lee JS, Gonik AM, Dong T, Fung G, Sanchez E, Xing L, Cheng HR, Luo J, and Lam KS. "OA02" Peptide Facilitates the Precise Targeting of Paclitaxel-Loaded Micellar Nanoparticles to Ovarian Cancer In Vivo. Cancer Research. 72(8): 2100-2110, 2012. (PMID: 22396491)
  145. Skokeen M, Zheleznyak A, Wilson JM, Jiang M, Liu R, Ferdani R, Lam KS, Schwarz, Anderson CJ. Molecular imaging of very late antigen-4 (α4β1 integrin) in the premetastatic niche. The Journal of Nuclear Medicine, 53: 779-786, 2012. (PMDI 22496586)
  146. Zhang H, Luo J, Li Y, Henderson PT, Wang Y, Wachsmann-Hogiu S, Zhao W, Lam KS, Pan C. Characterization of high-affinity peptides and their feasibility for use in nanotherapeutics targeting leukemia stem cells. Nanomedicine: Nanotechnology, Biology, and Medicine. In press, 2012. (PMDI: 22197725)
  147. Xiao W, Luo J, Jian T, Riggs J, Tseng H, Henderson PT, Cherry S, Rowland D, and Lam KS. The biodistribution and pharmacokinetics of a telodendrimer micellar paclitaxel nano-formulation in an ovarian cancer mouse xenograft model. International Journal of Nanomedicine. 7: 1587-1597, 2012.
  148. Li Y, Xiao W, Xiao K, Berti L, Luo J, Tseng HP, Gung G, and Lam KS. Well-Defined, Reversible Boronate Crosslinked Nanocarriers for Targeted Drug Delivery in Response to acidic pH and cis-Diols. Angewandte Chemie Int Ed Engl. 51: 2864-2869, 2012. (PMID: 22253091)
  149. Lin T, Zhang H, Luo J, Li Y, Gao T, Lara PN, de Vere White R, Lam KS, and Pan CX. Multifunctional targeting micelle nanocarriers with both imaging and therapeutic potential for bladder cancer. International Journal of Nanomedicine. 7: 2793-2804, 2012.
  150. Guan M, Yao W, Liu R, Lam KS, Nolta J, Jia J, Ranganiban B, Meng L, Zhou P, Shahnazari M, Ritchie RO, and Lane NE. Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass. Nature Medicine. 18: 456-462, 2012. (PMID: 22306732)
  151. Aina OH, Maeda Y, Harison M, Zwingenberger AL, Walker NJ, Lam KS, and Kent MS. Canine malignant melanoma alpha-3 integrin binding peptides. Vet immunol immunopathol. 143:11-19, 2011. (PMID: 21722969)
  152. Naiyanetr P, Butler JD, Meng L, Pfeiff J, Kenny TP, Guggenheim KG, Reiger R, Lam KS, Kurth MJ, Ansari AA, Coppel RL, Lopez-Hoyos M, Gershwin ME, Leujng PSC. Electrophile-Modified Lipoic Derivatives of PDC-E2 Elicits Anti-mitochondrial Antibody Reactivity. Journal of Autoimmunity. 37:209-216, 2011.
  153. Yao N, Chen CY, Wu CY, Motonishi K, Kung HJ, Lam KS. Novel flavonoids with anti-proliferative activities against breast cancer cells. J of Medicinal Chemistry, 54: 4339-4349, 2011.
  154. Xiao K, Luo J, Li Y, Lee JS, Fung G, Lam KS. PEG-oligocholic acid telodendrimer micelles for the targeted delivery of doxorubicin to B-cell lymphoma. Journal of Controlled Release. 155: 272-281, 2011.
  155. Li Y, Xiao K, Luo J, Xiao W, Lee JS, Gonik AM, Kato J, Dong T, and Lam KS. Well-defined, Reversible Disulfide Cross-linked Micelles for On-demand Paclitaxel Delivery. Biomaterial. 32: 6633-6645, 2011.
  156. Shi L, Fleming CJ, Riechers SL, Yin NN, Luo J, Lam KS, Liu GY. High-Resolution Imaging of Dendrimers Used in Drug Delivery via Scanning Probe Microscopy. Journal of Drug Delivery. Jun13. 2011.
  157. Kawano M, Xing L, Hand H, Miyamura T, Barnett S, Srivastava I, Lam KS, Cheng H. Design platforms of nanocapsules for human therapeutics or vaccines. In Development of Vaccines, from discovery to clinical testing, ed Singh M and Srivastava I. Wiley, pp125-140, 2011, 2011.
  158. Chang PC, Fitzgerald LD, Hsia DA, Izumiya Y, Wu CY, Hsieh WP, Lin SF, Campbell M, Lam KS, Luciw PA, Tepper CG, Kung HJ. Histone demethylase JMJD2A regulates KSHV replication and is targeted by a viral transcriptional factor. J Virol. 85: 3283-3293, 2011.
  159. Ding Y, Hong L, Nie B, Lam KS, Pan T. Capillary-driven automatic packaging. Lab on a Chip. 11: 1464-1469, 2011.
  160. Xiao K, Li Y, Luo J, Lee JS, Xiao W, Gonik AM, Agarwal RG, Lam KS. The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles. Biomaterials. 32: 3435-3446, 2011.
  161. Kumaresan P, Wang Y, Saunders M, Maeda Y, Wang X, Liu R, Lam KS. Rapid Discovery of Death Ligands with One-Bead-Two-Compound Combinatorial Library Methods. Journal of Combinatorial Sciences. 13: 259-264, 2011.
  162. Li J, Liu R, Lam KS, Jin LW, Duan Y. Alzheimer’s disease drug candidates stabilize A-beta protein native structure by interacting with the hydrophobic core. Biophysical Journal. 100: 1076-1082, 2011.
  163. Deane S, Yao N, Lam KS. On Arrows and traps: The use of the one-bead-one-compound combinatorial library method to identify cell surface targeting ligands; in Targeted Drug Delivery in Cancer Therapeutics. Ed. Michael A Firer. Transworld Research Network, Kerala, India. 2101: 85-125.
  164. Berti L, Woldeyesus T, Li Y, Lam KS. Maximization of loading and stability of ssDNA:iron oxide nanoparticle complexes formed through electrostatic interaction. Langmuir. 26:18293-18299, 2010.
  165. Zhang H, Aina O, Lam KS, de Vere White R, Evans C, Henderson P, Lara P, Wang X, Bassuk JA, Pan C. Identification of a bladder cancer-specific ligand using a combinatorial chemistry approach. Urologic Oncology: Seminars and Original Investigations. In press, 2010.
  166. Xiao W, Wang Y, Lau EY, Luo J, Yao N, Shi C, Meza L, Tseng H, Maeda Y, Kumaresan P, Liu R, Lightstone FC, Takada Y, and Lam KS. The use of one-bead one-compound combinatorial library technology to discover high-affinity αv3integrin and cancer targeting RGD ligands with a build-in handle. Mol Cancer Ther. 10: 2714-2723, 2010.
  167. Carpenter RD, Natarajan A, Lau EY, Andrei M, Solano DM, Lightstone FC, DeNardo SJ, Lam KS, Kurth MJ. Halogenated benzimidazole carboxamides target integrin alpha4beta1 on T-cell and B-cell lymphomas. Cancer Research. 70: 5448-556, 2010.
  168. Yao N, Fung G, Malken H, Ye L, and Lam KS. Facile synthesis of glycosylated Fmoc amino acid building blocks assisted by microwave irradiation. Carbohydrate Research. 345: 2277-2281, 2010.
  169. Townsend JB, Shaheen F, Liu R, Lam KS. Jeffamine Derivatized TentaGel Beads and PDMS Microbead Cassettes for Ultra-high Throughput in situ Releasable Solution-Phase Cell-based Screening of OBOC Combinatorial Small Molecule Libraries. J Combinatorial Chemistry. 12: 700-712, 2010.
  170. Luo J, Xiao K, Lo Yuanpei, Lee JS, Shi L, Tan YH, Xing L, Cheng H, Liu GY, Lam KS. Well-defiend, size-tunable, multi-functional micelles for efficient paclitaxel delivery for cancer treatment. Bioconjugate Chemistry. 21: 1216-1224, 2010.
  171. Liu R, Aina OH, Onofiok E, and Lam KS. The “One-Bead-One-Compound” Combinatorial Approach to Identifying Molecular Imaging Probes. In Molecular Imaging, Principles and Practice, People’s Medical Publishing House – USA, ed Weissleder, Ross, Rehemtulla, and Gambhir, pp481-496, 2010.
  172. Xiao K, Luo J, Li Y, Xiao W, Gonik AM, and Lam KS. The passive targeting of polymeric micelles in various types and sizes of tumor models. Nanoscience and Nanotechnology Letters. In press, 2010.
  173. Xiang B, Sun G, Lam KS, Xiao K. Novel poly(ethylene-co-acrylic acid) nanofibrous biomaterials for peptide synthesis and biomedical applications. Journal of Biomedical Materials Research. 95:245-255, 2010.
  174. Wu Z, Chang PC, Yang JC, Chu CY, Ling-Yu Wang LY, Chen NT, Ma AH, Desai SJ, Lo SH, Evans CP, Lam KS, and Kung HJ. Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors. Genes and Cancer. 1:40-49, 2010.
  175. Fei YY, Landry JP, Sun YS, Zhu X, Wang X, Luo J, Wu CY, Lam KS. Screening small-molecule compound microarrays for protein ligands without fluorescence labeling with a high-throughput scanning microscope. J Biomed Opt. Jan-Feb, 2010.
  176. Townsend J, Do A, Lehman A, Dixon S, Sanii B, Lam KS. 3-Nitro-tyrosine as an internal quencher of autofluorescence enhances the compatibility of fluorescence based screening of OBOC combinatorial libaries. Comb Chem High Throughput Screen. 13: 422-429, 2010.
  177. Li Y, Xiao K, Luo J, Lee J, Pan S, Lam KS. A novel size-tunable nanocarrier system for targeted anticancer drug delivery. Journal of Controlled Release, 144: 314-323, 2010.
  178. Maverakis E, Menezes JS, Ametani A, Han M, Stevens DB, Yong Y, Yoko O, Miyamura Y, Lam KS, Ward ES, Sercarz EE. Molecular mimics can induce a nonautoaggressive repertoire that pre-empts induction of autoimmunity. Proc of Nat Acad Sci, 107: 2550-2555, 2010.
  179. Despa F, Luo JT, Li J, Duan Y, Lam KS. Cholic acid micelles – controlling the size of the aqueous cavity by PEGylation. Phys Chem Chem Phys. 12: 1589-1594, 2010.
  180. Chang PC, Izumiya Y, Wu CY, Fitzgerald LD, Campbell M, Ellison T, Lam KS, Luciw PA, Kung HJ. Kaposi's sarcoma associated herpesvirus (KSHV) encodes a SUMO E3 ligase which is SIM-dependent and SUMO-2/3-specific. J Bio Chem, 285:5266-5273, 2010.
  181. Zhu M, Baek H, Liu R, Song A, Lam KS, and Lau D. LAS0811: From combinatorial chemistry to activation of antioxidant response element (ARE). Journal of Biomedicine and Biotechnology. 2009: 420194, 2009.
  182. Kappel JC, Fan YC, Lam KS. Application of the “libraries from libraries” concept to “one-bead one-compound” combinatorial chemistry. Adv Exp Med Biol. 611: 21-22, 2009.
  183. Luo H, Onofiok E, Shi C, Liu R, and Lam KS. A novel hydrogel functionalized with specific peptidomimetic ligands for 2-D and 3-D cell culture. Adv Exp Med Biol. 611:19-20, 2009.
  184. Yao N, Xiao W, Meza L, Tseng H, Chuck M, Lam KS. Structure-activity relationship studies of targeting ligands against breast cancer cells. J Med Chem. 52:6744-6751, 2009.
  185. Nair R, Emmons MF, Cress AE, Argilagos RF, Lam KS, Kerr WT, Wang HG, Dalton WS, Hazlehurst LA. HYD1-induced increase in reactive oxygen species leads to autophagy and necrotic cell death in multiple myeloma cells. Mol Cancer Ther, 8:2441-2451, 2009.
  186. Bei X, Lam KS and Sun G. Functional fibrous polypropylene solid support and its application in solid phase peptide synthesis and cell specific binding. Reactive & Functional Polymers. 69: 905-914, 2009.
  187. Xiao K, Luo J, Fowler W, Li Y, Lee JS, Xing L, Cheng RH, Wang L and Lam KS. A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer. Biomaterial. 30:6006-6016, 2009.
  188. Hong HS, Maezawa I, Budamagunta M, Rana S, Shi A, Vassar R, Liu RW, Lam KS, Cheng H, Hua DH, Voss JC, Jin LW. Candidate anti-Aβ fluorine compounds selected from analogs of amyloid imaging agents. Neurobiology of Aging, Nov 18 2009
  189. Saegusa J, Yamaji S, Ieguchi K, Wu CY, Lam KS, Liu FT, Takada YK, Takada Y. The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphaVbeta3 is involved in IGF-1 signaling. J Biol Chem. 284:24106-24114, 2009.
  190. Yao N, Xiao W, Wang X, Marik J, Park SH, Takada Y, Lam KS. Discovery of targeting ligands for breast cancer cells using the one-bead one-compound combinatorial method. J Med Chem 52: 126-133, 2009.
  191. Sun YS, Landry JP, Fei YY, Zhu XD, Luo JT, Wang XB, Lam KS. Macromolecular scaffolds for immobilizing small molecule microarrays in label-free detection of protein-ligand interactions on solid support. Anal Chem, 81: 5373-5380, 2009.
  192. Kim TH, Venugopal SK, Zhu M, Wang SS, Lau D, Lam KS, Clemens DL, Zern MA. A novel small molecule, LAS-0811, inhibits alcohol-induced appptosis in VL-17A cells. Biochemical and Biophyscial Research Communications, 379: 876-81, 2009.
  193. Kenyon NJ, Liu R, O’Roarck, Huang W, Peng L, and Lam KS. An a4b1 integrin antagonist decreases airway inflammation in ovalbumin-exposed mice. European Journal of Pharmacology, 603:138-46, 2009.
  194. Carpenter RD, Andrei M, Aina OH, Lau E, Lightstone F, Liu R, Lam KS, Kurth MJ. Selectively Targeting T- and B-cell Lymphomas: A Benzimidazole antagonist of α4β1 Integrin. J Med Chem 52: 14-19, 2009.
  195. DeNardo SJ, Natarajan A, Albrecht H, Liu R, Peng L, Sutcliffe JL, Yuan A, Cherry SR, Lam KS. 111In-LLP2A-DOTA Polyethylene Glycol–Targeting α4β1 Integrin: Comparative Pharmacokinetics for Imaging and Therapy of Lymphoid Malignancies. Journal of Nuclear Medicine. 50: 625-34, 2009.
  196. Kumaresan PR, Luo J, Lam KS. On-demand cleavable linkers for radioimmunotherapy. Methods Mol Biol. 539:191-211, 2009
  197. Park SH, Wang X, Liu R, Lam KS, Weiss RH. High throughput screening of a small molecule one-bead-one-compound combinatorial library to identify attenuators of p21 as chemotherapy sensitizers. Cancer Biology & Therapy. 7: 2015-2022, 2009.
  198. de Looz ML, An HJ, Kronewitter S, Kim J, Beecroft S, Vinall R, Miyamoto S, deVere White R, Lam KS, Lebrilla C. Glycomic approach for potential biomarkers on prostate cancer: Profiling of N-linked glycans in human sera and pRNS cell lines. Disease Markers 25: 243-258, 2008.
  199. Varela MC, Dixon SM, Lam KS, Schore NE. Asymmetric epoxidation, Michael addition, and triple cascade reaction suing polymer-supported prolinol-based auxiliaries. Tetrahedron, 64:10087, 2008.
  200. Li B, An HJ, Kirmiz C, Lebrilla CB, Lam KS, Miyamoto S. Glycoproteomic analyses of ovarian cancer cell lines and sera from ovarian cancer patients with distinct glycosylation changes in individual proteins. J Proteome Res, 7:3776-3788, 2008.
  201. Saegusa J, Akakura N, Wu CY, Hoogland C, Ma Z, Lam KS, Liu FT, Takada YK, Takada Y. Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner. J Biol chem., 283:26170-26175, 2008.
  202. Hong HS, Maezawa I, Budamagunta M, Rana S, Shi A, Vassar R, Liu R, Lam KS, Cheng RH, Hua DY, Voss JC, Jin LW. Candidate anti-Ab fluorine compounds selected from analogs of amyloid imaging agents. Neurobiology of Aging. In press, 2008.
  203. Pearson D, O’Donnell RT, Cerejo M, McKnight HC, Wang X, Marik J, Lam KS, and Tuscano JM. CD22-binding peptides derived from anti-CD22 ligand blocking antibodies retain the targeting and cell killing properties of the parent antibodies and may serve as a drug delivery vehicle. Int J Pept Res Ther, in press, 2008.
  204. Baek HG, Liu R, and Lam KS. Development of Hydrogel TentaGel Shell-Core Beads for Ultra-high Throughput Solution Phase Screening of Encoded OBOC Combinatorial Small Molecule Libraries. J Comb Chem, 11:91-102, 2008.
  205. Sun YS, Landry JP, Fei YY, Zhu XD, Luo JT, Wang XB, Lam KS. Effect of fluorescently labeling protein probes on kinetics of protein-ligand reaction. Langmuir, 24: 13399-13405, 2008.
  206. Natarajan A, Kumaresan PR, DeNardo SJ, DeNardo GL, Mirick G, and Lam KS. Development of TNKase Specific Cleavable Peptide-Linked Radioimmunoconjugates for Radioimmunotherapy. Bioorganic & Medicinal Chemistry Letter, 18:4802-4805, 2008.
  207. Xiao W, Yao N, Peng L, Liu R, Lam KS. Near-infrared optical imaging in glioblastoma xenograft with ligand targeting a3 integrin. European Journal of Nuclear Medicine and Molecular Imaging, 36: 94-103, 2008.
  208. Wakabayashi K, Lian ZX, Leung PS, Moritoki Y, Tsuneyama K, Kurth MJ, Lam KS, Yoshida K, Yang GX, Hibi T, Ansari AA, Ridgway WM, Coppel RL, Mackay IR, Gershwin ME. Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease. Hepatology, 48: 531-540, 2008.
  209. Carpenter RD, Fettinger JC, Lam KS, and Kurth MJ. Asymmetric catalysis: resin-bound hydroxylprolylthreonine derivatives in enamine-mediated reactions. Angew. Chem. Int. Ed. 47: 6407-6410, 2008.
  210. Luo J, Zhang H, Xiao W, Kumaresan PR, Shi Cm Pan C, Aina O, Lam KS. Rainbow Beads: A Color Coding Method to Facilitate High-Throughput Screening and Optimization of One-Bead One-Compound Combinatorial Libraries. Journal of Combinatorial Chemistry, 10:599-604, 2008.
  211. Li B, An HJ, Kirmiz C, Lebrilla C, Lam KS, and Miyamoto S. Glycoproteomic analyses of ovarian cancer cell lines and sera from ovarian cancer patients show distinct glycosylation changes in individual proteins. Journal of Proteome Research, 7: 3776-3788, 2008.
  212. Kumaresan PR, Juntao L, Song A, Marik J, and Lam KS. Evaluation of ketone-oxime method for developing therapeutic on-demand cleavable immunoconjugates. Bioconjugate Chemistry, 19: 1313-1318, 2008.
  213. Fei YY, Landry JP, Sun YS, Zhu XD, Luo JT, Wang XB, Lam KS. A novel high-throughput scanning microscope for label-free detection of protein and small-miolecule chemical microarrays. Rev Sci Instrum, 79: 13708, 2008.
  214. Mori S, Wu CY, Yamaji S, Saegusa J, Shi B, Ma Z, Kuwabara Y, Lam KS, Isseroff RR, Takada YK, Takada Y. Direct binding of integrin avb3 to FGF1 plays a role in FGF1 signaling. J Biol Chem, 283: 18066-75, 2008.
  215. Yao N, Wu C, Xiao W, Lam KS. Discovery of high affinity peptide ligands for Vancomycin. Peptide Sciences, 90:421-432, 2008.
  216. Peng L, Liu R, Andrei M, Xiao W, Lam KS. In vivo Imaging of Human Lymphoma Xenograft Using a Library-derived Fluorescent-labeled Peptidomimetic Ligand Against a4b1 Integrin. Molecular Cancer Therapeutics. 7:432-437, 2008.
  217. Liu, R, Lam KS. Combinatorial Peptide Libraries. Encyclopedia of Molecular Cell Biology and Molecular Medicine, R.A. Meyer ed.,Wiley-VCH Publisher, in press, 2007.
  218. Kappel J; Fan Y; Lam KS. Global Transformation of OBOC Peptide Libraries into OBOC Polyamine and Small Molecule Libraries. J Combinatorial Chemistry. 10:333-342, 2007.
  219. Miyamoto S, Liu R, Hung S, Wang X, and Lam KS. Focused screening of a one-bead one compound (OBOC) combinatorial library for beta-actin identifies small molecules with biological activity toward Ramos B lymphoma cells. Analytical Biochemistry. 374:112-120, 2007.
  220. Maezawa I, Hong HS, Liu R, Wu CY, Cheng RH, Kung MP, Kung HF, Lam KS, Oddo S, Laferla FM, and Jin LW. Congo red and thioflavin-T analogs detect Abeta oligomers. J Neurochem. 104:457-468, 2007.
  221. Carpenter RD, Mirela A, Lau EY, Lightstone FC, Liu R, Lam KS, Kurth MJ. Highly potent, water soluble benzimidazole antagonist for activated a4b1 integrin. J Medicinal Chemistry. 50: 5863-5867, 2007.
  222. Aina OH, Liu R, Sutcliffe-Goulden JL, Marik J, Pan C, and Lam KS.From Combinatorial Chemistry to Cancer Targeting Peptides. Molecular Pharm. 4:631-651, 2007.
  223. Zhu X, Landry JP, Sun YS, Gregg JP, Lam KS, Guo X. Oblique-incidence reflectivity difference microscope for label-free high-throughput detection of biochemical reactions in a microarray format. Applied Optics. 48: 1890-1895, 2007.
  224. Leung PSC, Park O, Tsuneyama K, Kurth M, Lam KS, Ansari AA, Coppel RL, Gerhswin ME.Induction of Primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization. The Journal of Immunology. 179: 2651-2657, 2007.
  225. Hartmann-Siantar CL, DeNardo GL, Lam KS, Yuan A, Daly T, and DeNardo SJ. Selecting an intervention time for intravascular enzymatic cleavage of peptide linkers to clear radioisotope from normal tissues. Cancer Biotherapy & Radiopharmaceuticals. 22: 556-563, 2007.
  226. Leiseowitz GS, Lebrilla C, Miyamoto S, An HJ, Duong H, Kirmiz C, Li B, Liu H, Lam KS. Glycomics analysis of serum: a potential new biomarker for ovarian cancer. Int J Gynecol Cancer, 18:470-475, 2007.
  227. Carpenter R, Lam KS, Kurth MJ. Microwave-mediated heterocyclization to benzimidazo[2,1-b]quinazlin-12(5H)-ones. Journal of Organic Chemistry, 72: 284-287, 2007.
  228. Hong HS, Maezawa I, Yao N, Xu B, Diaz-Avalos R, Rana S, Hua DH, Cheng RH, Lam KS, Jin LW. Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Ab oligomer-indcued cytotoxicity. Brain Research 30: 223-234, 2006.
  229. Izumiya Y, Izumiya C, Van-Geelen A, Wang DH, Lam KS, Luciw PA, and Kung HJ. Kaposi’s sarcoma-associated herpesvirus endcoded protein kinase (vPK) and its interaction with K-bZIP. Journal of Virology, 81: 1072-82, 2006.
  230. Kumaresan PR, Arutselvan N, Song A, Wang X, DeNardo G, DeNardo S, and Lam KS. The development of tissue plasminogen activator specific “On Demand Cleavable” (ODC) linkers for radioimmunotherapy by screening one bead one compound combinatorial peptide libraries. Bioconjugate Chemistry, 18: 175-82, 2006.
  231. Kirmiz C, Li B, An HJ, Clowers BH, Chew HK, Lam KS, Ferrige A, Alecio R, Borowsky AD, Sulaimon S, Lebrilla CB, and Miyamoto S. A serum glycomics approach to breast cancer biomarkers. Molecular and Cellular Proteomics, 6: 43-55, 2006.
  232. Sroka T, Marik J, Lam KS, and Cress A. The Minimum Element of a Synthetic Peptide Required to Block Prostate Tumor Cell Migration. Cancer Biology & Therapy, 5: 1556-62, 2006.
  233. Dixon SM, Milinkevich KA, Fujii J, Liu R, Yao N, Lam KS, Kurth M. A spiroisoxazolinoproline-based amino acid scaffold for solid phase and one-bead one-compound library synthesis. Journal of Combinatorial Chemistry, 9: 143-57, 2006.
  234. Carpenter R, Lam KS, Kurth M. Carbodiimide-Based Benzimidazole Library Method. Journal of Combinatorial Chemistry, 8: 907-914, 2006.
  235. Dixon S, Lam KS, Kurth M. Aminodeoxychorismate Synthase Inhibitors From One-Bead One-Compound Combinatorial Libraries: “staged” inhibitor design. Journal of Medicinal Chemistry, 49: 7413-7426, 2006.
  236. Liu R, Peng L, Han H, and Lam KS. Structure-activity relationship studies of a series of peptidomimetic ligands for α4β1 integrin on Jurkat T-leukemia cells. Biopolymers (Peptide Science) 84: 595-604, 2006.
  237. Lehman A, Gholami S, Hahn M, Lam KS. Novel image subtraction approach to screening one-bead one-compound combinatorial libraries with complex protein mixtures. Journal of Combinatorial chemistry, 8:562-570, 2006.
  238. An HJ, Miamoto S, Lancaster KS, Kirmiz C, LI B, Lam KS, Leiserowitz, and Lebrilla CB. Profiling of Glycans in serum for the Discovery of Potential Biomarkers for Ovarian Cancer. Journal of Proteome Research, 5:1626-1635, 2006.
  239. Reiger R, Leung PS, Jeddeloh MR, Kurth MJ, Nantz MH, Lam KS, Barsky D, Ansari AA, Coppel RL, Mackay JR, Gershwin ME. Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis. J Autoimmun. 27: 7-16, 2006.
  240. Kumaresan P, Lam KS. Screening Chemical Microarrays: methods and applications. Exploiting Chemcial Diversity for Drug Discovery, ed by Barlett and Entzeroth, RSC publishing, pp291-312, 2006; Mol Biosyst. 2: 259-70, 2006.
  241. Peng L, Liu R, Marik J, Wang X, Takada Y, Lam KS. Combinatorial Chemistry Identifies High-Affinity Peptidomimetics against a4b1 Integrin. Nature Chemical Biology, 2: 381-389, 2006.
  242. Lau D, Guo L, Liu R, Marik J, Lam KS. Peptide ligands targeting integrin a3b1 in non-small cell lung cancer, Lung Cancer, 52: 291-297, 2006.
  243. Song A., Wu L, Ho L, Lam KS. Facile solid-phase synthesis of 2,3-disubstituted 6H-pyrano[2,3-f]benzimidazole-6-ones. Tetrahedron, 62: 4393-4399, 2006.
  244. Liu R, Wang X, Song A, Bao T, Lam KS. Development and applications of topologically segregated bilayer beads in one-bead one-compound combinatorial libraries. QSAR Combi. Sci., 24: 1127-1140, 2005.
  245. Aina OH, Marik J, Gandour-Edwards R, Lam KS. Near-infrared optical imaging of ovarian cancer xenografts with novel a3-integrin binding peptide “OA02”. Molecular Imaging, 4: 439-447, 2005.
  246. Dixon S, Wang X, Lam KS, and Kurth M. Solid phase synthesis of quinoxaline, thiazine and oxazine analogs through a benzyne intermediate. Tetrahedron Letter, 46: 7443-7446, 2005.
  247. Wang X, Dixon S, Kurth M, and Lam KS. Microwave assisted DIC-promoted intramolecular cyclization for solid phase synthesis of trisubstituted imidazolidinones and pyrimidinones. Tetrahedron Letter, 46:5361-5364, 2005.
  248. Wang X, Dixon S, Kurth M, and Lam KS. Traceless solid phase synthesis of 1,4-disubstituted-6-nitro-3,4-dihydro-1H-quinoline-2-ones. Tetrahedron Letter, 46: 5361-5364, 2005.
  249. Gillies RJ, Hoffman JM, Lam KS, Menkens AE, Piwnica-Worms DR, Sullivan J, and Weissleder R. Meeting Report: High-Throughput Technologies for In vivo Imaging Agents. Molecular Imaging, 4: 1-6, 2005.
  250. Dixon S, Robins L, Elling RA, Liu R, Lam KS, Wilson DK, and Kurth M. Discovery of Selective Aldose Reductase Ligands – An On-Bead Assay Strategy. Bioorganic and Medicinal Chemistry Letters, 15: 2938-2942, 2005.
  251. Aina O, Marik J, Liu R, Lau DH, and Lam KS: Identification of novel targeting peptides for human ovarian cancer cells using OBOC combinatorial libraries. Molecular Cancer Therapeutics, 4: 806-813, 2005.
  252. Amano K, Leung PSC, Rieger R, Quan C, Wang X, Marik J, Suen YF, Kurth MJ, Nantz MH, Ansari AA, Lam KS, Zeniya M, Matsuura E, Coppel RL, Gershwin ME. Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: Identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid. Journal of Immunology, 174: 5874-5883, 2005.
  253. Yao NH, Liu G, He WY, Niu C, Carlson JR, Lam KS, Solid-phase synthesis and antibacterial evaluations of N-demethylvancomycin derivatives. Bioorganic and Medicinal Chemistry Letters, 15: 2325-2329, 2005.
  254. Ying L, Liu R, Zhang J, Lam KS, Lebrilla CB, and Gervay-Hague J. A Topologically Segregated One-Bead-One-Compound Combinatorial Glycopeptide Library for Identification of High-Affinity Lectin Ligands. Journal of Combinatorial Chemistry, 7:372-384, 2005.
  255. Wang X, Peng L, Liu R, Gill SS, Lam KS. Partial Alloc-Deprotection Approach for Ladder Synthesis of “One-Bead One-Compound” Combinatorial Libraries. Journal of Combinatorial Chemistry, 7: 197-209, 2005.
  256. Wang X, Song A, and Lam KS. Facile solid phase synthesis of 1, 2-disubstituted-6-nitro-1,4-dihydro-quinazolines using a tetrafunctional scaffold. Tetrahedron Letters, 46: 427-430, 2005.
  257. Wang X, Peng L, Liu R, Xu B, and Lam KS. Application of topologically segregated bi-layer beads in “one-bead one-compound” combinatorial libraries. The Journal of Peptide Research, 65:130-138, 2005.
  258. Liu, R, Lam KS. Synthetic peptide and nonpeptide libraries. Encyclopedia of Molecular Cell Biology and Molecular Medicine, Volume 10, second edition, R.A. Meyer ed.,Wiley-VCH Publisher, pp147-176, 2005.
  259. Lam KS, Liu R, Marik J, Kumaresan P. From one-bead one-compound combinatorial libraries to chemical microarrays. Volume II: Micro/Nano Genomics and Proteomics" in "Biomems and Biomedical Nanotechnology" Encyclopedia by Kluwer. Submitted/invited, in press, 2005.
  260. Marik J, Lam KS. Peptide and small-molecule microarrays. Methods in Molecular Biology, Vol 310, Chemical Genomics: reviews and protocols, Ed Edward D. Zanders, Humana Press, pp217-226, 2005
  261. Yao N-H, He W-Y, Lam KS, Liu, G. Conformational studies of resin-bound vancomycin and the complex of vancomycin and Ac2-L-Lys-D-Ala-D-Ala. Journal of Combinatorial Chemistry, 7: 123-129, 2005.
  262. Hwang SH, Lehman A, Cong X, Olmstead MM, Lam KS, Lebrilla CB, and Kurth M. OBOC Small Molecule Combinatorial Library Encoded by Halogenated Mass-Tags. Organic Letters, 21: 3829-3832, 2004.
  263. Mikawa M, Wang H, Liu R, Lam KS, Lau DH. Novel peptide ligands for a4b1 integrin over-expressed in bronchiolalveolar cancer cells. Molecular Cancer Therapeutics, 3: 1329-1334, 2004.
  264. Katsushi A, Leung PSC, Xu Q, Marik J, Quan C, Kurth MJ, Nantz MH, Ansari AA, Lam KS, Zeniya M, Coppel RL, Gershwin ME. Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible. The Journal of Immunology, 172: 6444-6452, 2004.
  265. Martel CL, Li Y, Beckett L, Chew H, Christensen S, Davies A, Lam KS, Lau DH, Meyers FJ, O’Donnell R, Richman C, Scudder S, Tanaka M, Tsucano J, Welborn J, Wun T, Gandara DR, and Lara PN. Cancer clinical trial accrual patterns: a prospective re-evaluation of barriers to enrollment following passage of legislation requiring third-party payer coverage of cancer clinical trial costs in California. The Cancer Journal, 10: 294-300, 2004.
  266. Song A, Zhang J, Lebrilla CB, Lam KS. Solid-phase synthesis and spectral properties of 2-alkylthio-6H-pyrano[2,3-f]benzimidazole-6-ones: a combinatorial approach for 2-alkylthioimidazocoumarins. Journal of Combinatorial Chemistry 6:604-610, 2004.
  267. Song A, Lam KS. Parallel solid-phase synthesis of 2-arylamino-6H-pyrano[2,3-f]benzimidazole-6-ones. Tetrahedron 60:8605-8612, 2004.
  268. Song A, Lam KS. Solid-phase synthesis of 3-alkyl-2-arylamino-3,4-dihydroquinazolines. Tetrahedron Letters, 45: 2727-2730, 2004.
  269. Yao NH, He WY, Lam KS, and Liu G. Solid-phase synthesis of o-glycosylated Fmoc protected amino acids and quantitation by high resolution magic angle spinning NMR (HR/MAS NMR). The Journal of Combinatorial Chemistry, 6: 214-219, 2004.
  270. Wang X, Zhang J, Song A, Lebrilla CB, and Lam KS. Encoding method for OBOC small molecule libraries using a biphasic approach for ladder-synthesis of coding tags. J Am Chem Soc , 126: 5740-5749, 2004.
  271. Song A, Wang X, Zhang J, Marik J, Lebrilla CB, and Lam KS. Synthesis of hydrophilic and flexible linkers for peptide derivatization in solid phase. Bioorganic and Medicinal Chemistry Letters, 14: 161-165, 2004.
  272. Enstrom AM, Lam KS. Characterization of peptides that selectively bind neuroendocrine differentiated prostate cancer cells. In Peptide Revolution: Genomics, Proteomics & Therpaeutics (Proceedings of the Eighteenth American Peptide Symposium July 19-23, 2003), Chorev, M and Sawyer, T. (eds), pp. 845-846, 2004.
  273. Song A, Zhang J, Lebrilla CB, Lam KS. A Novel encoding method for one-bead one-compound peptidomimetic and small molecule combinatorial libraries. In Peptide Revolution: Genomics, Proteomics & Therpaeutics (Proceedings of the Eighteenth American Peptide Symposium July 19-23, 2003), Chorev, M and Sawyer, T. (eds), pp. 843-844, 2004.
  274. Marik J, Lau H, Lam KS. Preparation and use of magnetic solid phase peptide synthesis supports. In Peptide Revolution: Genomics, Proteomics & Therpaeutics (Proceedings of the Eighteenth American Peptide Symposium July 19-23, 2003), Chorev, M and Sawyer, T. (eds), pp 100-101, 2004.
  275. Liu R, Lam KS. Increase diversity of sone-bead one-compound combinatorial peptide libraries with side-chain derivatization. In Peptide Revolution: Genomics, Proteomics & Therpaeutics (Proceedings of the Eighteenth American Peptide Symposium July 19-23, 2003), Chorev, M and Sawyer, T. (eds), pp. 847-848, 2004.
  276. Wang X, Peng L, Liu R, Lam KS. Application of topologically segregated bifunctional beads to construct unique combinatorial bead libraries. In Peptide Revolution: Genomics, Proteomics & Therpaeutics (Proceedings of the Eighteenth American Peptide Symposium July 19-23, 2003), Chorev, M and Sawyer, T. (eds), pp. 829-830, 2004.
  277. Liu R, Wang J, Marik J, Lam KS. An encoding method for one-bead one-compound beta-turn peptide and peptidomimetic libraries. In Peptide Revolution: Genomics, Proteomics & Therpaeutics (Proceedings of the Eighteenth American Peptide Symposium July 19-23, 2003), Chorev, M and Sawyer, T. (eds), pp. 388-389, 2004.
  278. Lam KS, Marik J, Xu Q. A Novel encoded high-density chemical microarray platform for proteomics and drug development. In Peptide Revolution: Genomics, Proteomics & Therpaeutics (Proceedings of the Eighteenth American Peptide Symposium July 19-23, 2003), Chorev, M and Sawyer, T. (eds), pp. 849-853, 2004.
  279. Liu R, Hsieh C, Lam KS: New approaches to identifying drugs to inactivate oncogenes. Seminar in Cancer Biology, 14: 13-21, 2004.
  280. Song A, Zhang J, Lam KS: Synthesis and reactions of 7-fluoro-6-nitro-4-methyl-2-0xo-2H-1-benzopyran-3-carboxylic acid: a novel scaffold for combinatorial synthesis of coumarins. J Combinatorial Chemistry, 6: 112-120, 2004.
  281. Xu Q, Miyamoto S, and Lam KS: A novel approach to chemical microarray using ketone-modified macromolecular scaffolds: application in micro cell-adhesion assay. Molecular Diversity, 8:301-310, 2004.
  282. Xu QC, Lam KS: Chemical microarray in proteomics. Journal of Biomedicine & Biotechnology, 5: 257-266, 2003.
  283. Kamath J, Liu R, Endstrom A, Qiang Lou, and Lam KS: Development and characterization of potent pseudosubstrate peptide inhibitors for p60c-src protein tyrosine kinase. The Journal of Peptide Research, 62: 260-268, 2003.
  284. DeNardo GL, DeNardo SJ, Peterson JK, Miers LA, Lam KS, Hartmann-Siantar C, Lamborn KR: Preclinical evaluation of cathepsin-degradable peptide linkers for radioimmunoconjugates. Clinical Cancer Research, 9:3865s-3872s, 2003.
  285. DeNardo SJ, Yao Z, Lam KS, Song A, Burke PA, Mirick GR, Lamborn KR, O’Donnell RT, DeNardo GL. Effect of Molecular Size of PEGylated peptide on the pharmacokinetics and tumor targeting in lymphoma bearing mice. Clinical Cancer Research, 9: 3854s-3864s, 2003.
  286. Lam KS, Lehman A, Song A, Doan N, Enstrom A, Liu R: Synthesis and screening of “one-bead one-compound” combinatorial peptide libraries. Methods in Ezymology, 369: 298-322, 2003.
  287. Liu R, Marik J, Lam KS: Design, synthesis, screening, and decoding of encoded one-bead one-compound peptidomimetic and small molecule combinatorial libraries. Methods in Ezymology, 369: 271-287, 2003.
  288. Leung PSC, Quan C, Park O, Van de Water J, Kurth MJ, Nantz MH, Ansari AA, Coppel RL, Lam KS, Gershwin, ME. Immunization with a xenobiotic 6-bromohexanoate BSA-conjugate induces antimitochondrial antibodies. J of Immunology, 170: 5326-5332, 2003.
  289. Marik J, Lau DH, Song A, Wang X, Liu R, and Lam KS. Magnetization of large polystyrene peptide beads for capturing and expanding cancer cells. Journal of magnetism and magnetic materials, 264: 153-157, 2003.
  290. Marik J, Song A, Lam KS. Detection of primary aromatic amines on solid phase. Tetrahedron letters, 44: 4319-4320, 2003.
  291. Lam KS, Liu R, Miyamoto S, Lehman A, Tuscano J: Applications of one-bead one-compound combinatorial libraries and chemical microarrays in signal transduction research. Accounts of Chemical Research, 36: 370-377, 2003.
  292. Song A, Zhang J, Lebrilla CB, Lam KS: A novel and rapid encoding method based on mass spectrometry for “one-bead-one-compound” small molecule combinatorial libaries. J American Chemical Society, 125: 6180-6188, 2003.
  293. Liu R, Enstrom A, and Lam KS: Combinatorial peptide library methods for immunobiology research. Experimental Hematology, 31: 11-30, 2003.
  294. Song, A, Wang X, Lam KS: A convenient synthesis of coumarin-3-carboxylic acids via Knoevenagel condensation of Meldrum’s acid with ortho-hydroxyaryl aldehydes or ketones. Tetrahedron Letters, 44: 1755-1758, 2003
  295. Franz A, H., Liu R, Song A, Lam KS, Lebrilla CB: High throughput one-bead-one-compound approach to peptide-encoded combinatorial libraries: MALDI-MS analysis of single tenta gel beads. Journal of Combinatorial Chemistry, 5: 125-137, 2003.
  296. Lam KS: Editorial: Peptides as Cancer Therapeutics. Biopolymers (Peptide Science), 66: 141, 2002.
  297. Aina OH, Sroka TC, Chen ML, and Lam KS: Therapeutic Cancer Targeting Peptides. Biopolymers (Peptide Science), 66: 184-199, 2002.
  298. Liu R, Marik J, and Lam KS: A novel peptide-based encoding system for “one-bead one-compound” small molecule combinatorial libraries. JACS, 124:7678-7680, 2002.
  299. Cheng W, Liu Y, Wong M, Lam KS, Kurth M: Stereoselective syntheses of unnatural spiroisoxazolinoproline-based amino acids and derivatives. J Organic Chemistry, 67: 5673-5677, 2002.
  300. Park SI, Manat R, Vikstrom B, Amro N, Song LW, Lam KS: The use of one-bead one-compound combinatorial library method to identify peptide ligands for a4b1 integrin receptor in non-Hodgkin’s lymphoma. Letters in Peptide Science, 8:171-178, 2002.
  301. Xu QC, Lam KS: An efficient approach to prepare glyoxylyl fucntionality on solid-support. Tetrahedron Letter, 43:4435-4437, 2002.
  302. Lau DH, Guo L, Liu R, Song A, and Lam KS: Identifying peptide ligands for cell surface receptors using cell-growth-on-bead assay and one-bead one-compound combinatorial library. Biotechnology Letters, 24:497-500, 2002.
  303. Nowick JS, Lam KS, Khasanova TV, Kemnitzer WE, Maitra S, Mee HT, Liu R: An unatural amino acid that induces b-sheet folding and interaction in peptides. JACS, 124: 4972-4973, 2002.
  304. Lam KS, and Renil M: From combinatorial chemistry to chemical microarray. Current Opinion in Chemical Biology, 6: 353-358, 2002.
  305. Wu J, Afar D, Witte ON, Lam KS: Recognition of multiple substrate motifs by the c-Abl protein tyrosine kinase. Combinatorial Chemistry & High Throughput Screening, 5: 83-91, 2002.
  306. Nagy SR, Liu G, Lam KS, Denison MS: Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay. Biochemistry, 41: 861-868, 2002.
  307. Park S, Manat R, Vikstrom B, Amro N, Lam KS: Identification of peptide ligands for a4b1 integrin receptor as potential targeting agents for non-Hodgkin's lymphoma. In Peptides: The wave of the future (Proceedings of the Second International and Seventeen American Peptide Symposium June 9-14, 2001), Lebl, M., Houghten RA (eds), Kluwer Academic Publishers, pp180-182
  308. Kamath JR, Liu R, Enstrom A, Liu G, Lou Q, Lam KS: Development and characterization of potent peptide inhibitors of p60c-srcPTK using pseudosubstrate-based inhibitor design approach. In Peptides: The wave of the future (Proceedings of the Second International and Seventeen American Peptide Symposium June 9-14, 2001), Lebl, M., Houghten RA (eds), Kluwer Academic Publishers, pp551-552.
  309. Kamath JR, Liu R, Enstrom AM, Liu G, Lam KS: Development of peptidomimetic substrates and inhibitors that bind to the peptide binding pocket of the catalytic site of p60c-src protein tyrosine kinase. In Peptides: The wave of the future (Proceedings of the Second International and Seventeen American Peptide Symposium June 9-14, 2001), Lebl, M., Houghten RA (eds), Kluwer Academic Publishers, pp183-184.
  310. Nowick JS, Lam KS, Gothard CM, Huon JK, Kemnitzer WE, Khasanova T, Kim HW, Liu R, Maitra S, Mee HT, Stigers KD. Designed amino acids that induce b-sheet folding and b-sheet interactions in peptides. In Peptides: The wave of the future (Proceedings of the Second International and Seventeen American Peptide Symposium June 9-14, 2001), Lebl, M., Houghten RA (eds), Kluwer Academic Publishers, pp572-574.
  311. Liu R, Lam KS: Structure elucidation of peptides with unnatural amino acids using an automated protein sequencer. In Peptides: The wave of the future (Proceedings of the Second International and Seventeen American Peptide Symposium June 9-14, 2001), Lebl, M., Houghten RA (eds), Kluwer Academic Publishers, pp299-300.
  312. Long SA, Quan C, Van de Water J, Nantz MH, Kurth MJ, Barsky D, Colvin ME, Lam KS, Coppel RL, Ansari A and Gershwin ME: Synthetic Organic/Peptide Conjugates Act as Mimeotopes of the Major Autoantigen of Primary Biliary Cirrhosis. J Immunology, 167:2956-2963, 2001.
  313. Liu R, Lam KS: Automatic Edman microsequencing of peptides containing many unnatural amino acids. Analytical Biochemistry, 295: 9-16, 2001.
  314. Falsey JR, Renil M, Park S, Li S, and Lam KS: Peptide and small molecule microarray for high-throughput cell adhesion and functional assays. Bioconjugate Chemistry, 12: 346-353, 2001.
  315. Migliaccio C, Van de Water J, Ansari AA, Coppel RL, Lam KS, Stevenson F, Gershwin ME: Heterogeneous response of antimitochondrial autoantibodies and bile duct apical staining monoclonal antibodies to pyruvate dehydrogenase complex E2: The molecule and the mimic. Hepatology, 33: 792-801, 2001.
  316. Miyashita M, Presley JM, Buchholz BA, Lam KS, Lee YM, Vogel JS, Hammock BD: Attomole level protein sequencing by Edman degradation coupled with accelerator mass spectrometry. Proc Natl Acad Sci, USA, 98: 4403-4408, 2001
  317. DeRoock IB, Pennington ME, Sroka TC, Lam KS, Bowden T, Bair EL, Cress AE: Synthetic peptides inhibit adhesion of human tumor cells to extracellular matrix proteins. Cancer Research, 61:3308-3313, 2001
  318. Lara P, Higdon R, Lim N, Kwan K, Tanaka M, Lau D, Wun T, Welborn J, Meyers F, Christensen S, O'Donnell R, Richman C, Scudder S, Tuscoano J, Gandara DR, Lam KS: A prospective evaluation of cancer clinical trials accrual patterns: identifying potential barriers to enrolment. J of Clinical Oncology, 19:1728-1733, 2001.
  319. Al-Obeidi F, Lam KS: Protein tyrosine kinase inhibitors. Oncogene 19: 5690-5701, 2000.
  320. Nagy S, Liu G, Lam KS, Denison MS: A green fluorescent protein based recombinaant cell bioassay for the detection of activators of the aryl hydrocarbon receptor: application for screening of a 1,5-dialkylamino-2,4-dinitrobenzene combinatorial chemical library. Organohalogen compounds, 45: 232-235, 2000.
  321. Liu G., Fan Y, Carlson JR, Zhao ZG, and Lam KS: Solution phase synthesis of a 1,5-dialkylamino-2,4-dinitrobenzene library and the identification of novel antibacterial compounds from this library. Journal of Combinatorial Chemistry, 2: 467-474, 2000.
  322. Liu G, Lam KS: One-bead one-compound combinatorial library method. In Combinatorial Chemistry, Practical Approach Series. Ed. B.D. Hames, IRL Press, pp 33-49, 2000.
  323. Falsey J, Li S, and Lam KS: Development of a chemical microarray technology. In Peptides: Chemistry, Structure and Biology (Proceedings of the Sixteen American Peptide Symposium June 26-July 1, 1999), Barany, G., Fields, G. and Tam, J. (eds), Kluwer Academic Publishers, pp 612-613, 2000.
  324. Liu G, Fan Y, Zhao D, Lam KS: Development of novel peptide antibiotics for vancomycin resistant infection using the "one-bead, one-compound" combinatorial library method. In Peptides: Chemistry, Structure and Biology (Proceedings of the Sixteen American Peptide Symposium June 26-July 1, 1999), Barany, G., Fields, G. and Tam, J. (eds), Kluwer Academic Publishers, pp 736-737, 2000.
  325. Zhao ZG, Im JS, Lam KS, Lake D: Site specific modification of a single chain antibody using a novel glyoxylyl-based labelling reagent. Bioconjugate chemistry, 10: 424-430, 1999
  326. Smith MH, Nuara A, Egen JE, Baradaran D, Lam KS, Grimes W: Baculoviral expressed HLA class I heavy chains used to screen a synthetic peptide library for allele-specific peptide binding motifs. Molecular Immunology, 35: 1033-1043, 1998
  327. Wu J, Afar D, Phan H, Witte ON, Lam KS. Bcr sequences are important for the intrinsic kinase activity and substrate specificity of Bcr-Abl oncoprotein. Bioorganic & Medicinal Chemistry Letters. 8:2279-2284, 1998
  328. Al-Obeidi F, Wu J, Lam KS: Protein Tyrosine Kinases: Structure, Substrate Specificity, and Drug Discovery. Peptide Science, 47: 197-223, 1998.
  329. Seligmann B, Lebl M, Lam KS: Solid-phase peptide synthesis, lead generation, and optimization. In Combinatorial Chemistry and Molecular Diversity in Drug Discovery, Gordon EM and Kerwin JF (eds) Wiley-Liss, pp39-109, 1998.
  330. Alfaro-Lopez J, Yuan W, Phan BC, Kamath J, Lou Q, Lam KS, Hruby VJ: Discovery of a novel series of potent and selective-based inhibitors of p60c-src protein tyrosine kinase: Conformational and topological constraints in peptide design. J. Med Chem. 41: 2252-2260, 1998.
  331. Miller TM, Chase EM, Dorr R, Dalton WS, Lam KS, Salmon SE: A phase I/II trial of paclitaxel for non-Hodgkin’s lymphoma followed by paclitaxel plus quinine in drug-resistant disease. Anti-Cancer Drugs 9:135-140, 1998.
  332. Lam KS, Sroka T. Chen ML, Zhao Y, Lou Q, Wu J, Zhao ZG: Application of “one-bead one-compound” library methods in signal transduction research. Life Sciences 17/18:1577-1583, 1998.
  333. Lam KS, Lou Q, Wu J, Leftwich M, McKay RT, Rychetsky L, Phan H, Joo J, Chen M-L, Liu-Stevens R, Zhao Y, Salmon SE: Application of the one-bead one-compound combinatorial library method in protein tyrosine kinase and cell surface receptor research. In: Peptides-Biology and Chemistry (Proceedings of the Chinese Peptide Symposium 1996), Escom, Leiden, pp55-58, 1997.
  334. Lam KS: Determination of peptide substrate motifs for protein kinases using a "one-bead one-compound" combinatorial library approach. Methods in Molecular Biology, Vol 87, Combinatorial Peptide Library Protocols, Ed Shmuel Cabilly, Humana Press, pp 83-86, 1997.
  335. Lam KS: Enzyme-linked colorimetric screening of a one-bead one-compound combinatorial library. Methods in Molecular Biology, Vol 87, Combinatorial Peptide Library Protocols, Ed Shmuel Cabilly, Humana Press, pp 7-12, 1997.
  336. Lam KS and Lebl M: Synthesis of a one-bead one-compound combinatorial peptide library. Methods in Molecular Biology, Vol 87,Combinatorial Peptide Library Protocols, Ed Shmuel Cabilly, Humana Press, pp 1-6, 1997.
  337. Lam KS and Zhao ZG: Targeted therapy for lymphoma with peptides. Hematology Oncology Clinics of North America 11:1007-1019, 1997.
  338. Lou Q, Leftwich M, McKay RT, Salmon SE, Rychetsky L, Lam KS: Potent pseudosubstrate-based peptide inhibitors for p60c-src protein tyrosine kinase. Cancer Research 57:1877-1881, 1997.
  339. Lam KS: Application of combinatorial library methods in cancer research and drug discovery. Anti-Cancer Drug Design 12:145-167, 1997.
  340. Lam KS, Krchnak V, Lebl M: The "one-bead one-compound" combinatorial library method. Chemical Reviews 97:411-448, 1997.
  341. Zhao ZG and Lam KS: Synthetic Peptide Libraries, in Annual Reports in Combinatorial Chemistry and Molecular Diversity, Vol 1, eds. Pavia M, Kay B, Ellington A, and Moos W, pp 192-209, Escom, Leiden, 1997.
  342. Wu J, Phan H, Salmon SE, Lam KS: Development of a selective inhibition of a pseudosubstrate-based peptide inhibitor of pp60c-src protein tyrosine kinase. Letters in Peptide Science 3:309-316, 1996.
  343. Salmon SE and Lam KS: Combinatorial chemistry for anticancer drug discovery. Anti-Cancer Drugs 7 (Suppl 3): 173-178, 1996.
  344. Krchnak V, Weichsel AS, Issakova O, Lam KS, Lebl M: Bifunctional scaffolds as templates for synthetic combinatorial libraries. Molecular Diversity 1: 177-182, 1996.
  345. Lebl M, Krchnak V, Patek M, Lam KS: Synthetic combinatorial libraries of scaffolded and unordered structures. Methods in Molecular and Cellular Biology 6: 41-55 (1995/1996).
  346. Lam KS and Lebl M: Synthesis and screening of a "one-bead one-compound" combinatorial peptide library. Methods in Molecular and Cellular Biology 6: 15-25 (1995/1996).
  347. Pennington ME, Lam KS, and Cress AE: The use of a combinatorial library method to isolate human tumor adhesion peptides. Molecular Diversity 2: 19-28, 1996.
  348. Hruby VJ, Shenderovich M, Lam KS, and Lebl M: Design considerations and computer modeling related to the development of molecular scaffolds and peptide mimetics for combinatorial chemistry. Molecular Diversity 2:46-56, 1996.
  349. Salmon SE, Liu-Stevens RH, Zhao Y, Lebl M, Krchnak V, Wertman K, Sepetov N, and Lam KS: High volume cellular screening for anticancer agents with combinatorial chemical libraries: A new methodology. Molecular Diversity 2: 57-63, 1996.
  350. Lou Q, Leftwich M, Lam KS: Identification of GIYWHHY as a novel peptide substrate for human p60c-src protein tyrosine kinase. Bioorganic and Medicinal Chemistry 4: 677-682, 1996.
  351. Chen CL, Strop P, Lebl M, Lam KS: One bead-one compound combinatorial peptide library, examples of three different types of screening. Methods in Enzymology 267: 211-219, 1996.
  352. Lebl M, Krchnak V, Strop P, Lam KS: Construction and screening of peptide and nonpeptide libraries based on one-bead-one-compound principle. In Peptides: Chemistry, Structure and Biology (Proceedings of the Fourteenth American Peptide Symposium), Kaumaya PTP and Hodges RS (eds), 890-892, 1996.
  353. Lam KS, Lou Q, Zhao ZG, Chen ML, Wade S, Salmon SE: Identification of idiotype-specific peptides for two murine B-cell lymphoma cell lines. In Peptides: Chemistry, Structure and Biology (Proceedings of the Fourteenth American Peptide Symposium), Kaumaya PTP and Hodges RS (eds) Mayflower Scientific Ltd, England, 806-807, 1996.
  354. Lam KS, Lou Q, Wu J, Salmon SE, Phan H: Identification of peptide substrates for various tyrosine protein kinases with the Selectide process. In Peptides: Chemistry, Structure and Biology (Proceedings of the Fourteenth American Peptide Symposium), Kaumaya PTP and Hodges RS (eds) Mayflower Scientific Ltd, England, 287-289, 1996.
  355. Lam KS and Lebl M: Combinatorial library based on the one-bead one-chemical concept. In Combinatorial Peptide and Nonpeptide Libraries - a handbook. Gunther Jung ed. VCH publishers, pp 173-201, 1996.
  356. Lam KS: Synthetic peptide and nonpeptide libraries. Encyclopedia of Molecular Biology and Molecular Medicine, Volume 5. R.A. Meyer ed.,VCH Publishers, pp 516-524, 1996.
  357. Lam KS, Lake D, Salmon SE, Smith J, Chen M-L, Wade S, Abdul-Latif F, Leblova Z, Ferguson RD, Krchnak V, Sepetov NF, Lebl M: Application of a one-bead, one-peptide combinatorial library method for B-cell epitope mapping. Methods: A Companion to Methods in Enzymology 9: 482-493, 1996.
  358. Vagner J, Barany G, Lam KS, Krchnak V, Sepetov NF, Ostrem JA, Strop P, Lebl M: Enzyme-mediated spatial segregation on individual polymeric support beads: Application to generation and screening of encoded combinatorial libraries. Proc Natl Acad Sci, USA 93: 8194-8199, 1996.
  359. Lou Q, Wu J, Lam KS: A protein kinase assay system for both acidic and basic peptides. Analytical Biochem. 235: 107-109, 1996.
  360. Krchnak V, Sepetov NF, Kocis P, Patek M, Lam KS, Lebl M: Combinatorial libraries of synthetic structures: Synthesis, screening, and structure determination. In: Combinatorial Libraries - synthesis, screening and application potential. Cortese R ed., Walter deGruyter, pp 27-52, 1996.
  361. Lou Q, Wu J, Salmon SE, Lam KS: Structure-activity relationship of a novel peptide substrate for p60c-src protein tyrosine kinase. Letters in Peptide Science 296-298 1995.
  362. Lebl M, Krchnak V, Sepetov NF, Nikolaev V, Stankova M, Kocis P, Patek M, Flegelova Z, Ferguson R, Lam KS: Synthetic combinatorial libraries. A new tool for drug design: Methods for identifying the composition of compound from peptide and/or nonpeptide libraries. In: Methods in Protein Structure Analysis, edited by Atassi MZ and Appella E. New York: Plenum Publishing, 1995, p 335-342.
  363. Seligman B, Abdul-Latif F, Al-Obeidi F, Flegelova Z, Issakova O, Kocis P, Krchnak V, Lam KS, Lebl M, Ostrem J, Safar P, Sepetov N, Stierandova A, Strop P, Wildgoose P: The construction and use of peptide and non-peptidic combinatorial libraries to discover enzyme inhibitors. Eur J Med Chem 30 (supplement); Proceedings of the XIIIth International Symposium on Medicinal Chemistry; Muller JC (Editor):319s-335s, 1995.
  364. Sepetov NF, Krchnak V, Stankova M, Lam KS, Wade S, Lebl M: Libraries of libraries - A novel approach in synthetic combinatorial libraries. In: Peptides - Biology and Chemistry. Lu GS., Tam, JP and Du YC (eds) (Proceedings of the Chinese Peptide Symposium 1994), Escom, Leiden, pp 271-272, 1995.
  365. Lam KS and Lebl M: Peptide library screening based on the one-bead one-peptide concept. In: Peptides - Biology and Chemistry, Lu GS., Tam, JP and Du YC (eds) (Proceedings of the Chinese Peptide Symposium 1994), Escom, Leiden, pp 273-277, 1995.
  366. Zhao Z-G and Lam KS: A novel approach for iodolabelling synthetic peptides. J. Chem. Soc., Chemical Communications, 1739-1740, 1995.
  367. Salmon SE, Lam KS, Felder S, Yeoman H, Schlessinger J, Ullrich A, Krchnak V, Lebl M: Use of large combinatorial chemical libraries for anticancer drug discovery. Int J Pharmacognosy, 33, Supplement, pp 67-74, 1995.
  368. Lam KS, Lebl M, Wu J, et al: Peptide library screening based on the one-bead one-peptide concept: An update. In Peptide 1994. Maia HLS ed., Escom, Leiden, pp 453-454, 1995.
  369. Flegelova Z, Krchnak V, Sepetov NF, Stankova M, Issakova O, Cabel D, Lam KS, Lebl M: Libraries of small compact structures N-acyl-N-alkylamino acids. In Peptide 1994. Maia HLS ed., Escom, Leiden, pp 469-470, 1995.
  370. Sepetov N, Krchnak V, Stankova M, Lam KS, Wade S, Lebl M: New approach in constructing and screening peptide libraries. In Peptide 1994. Maia HLS ed., Escom, Leiden, pp 467-468, 1995.
  371. Sepetov NF, Krchnak V, Stankova M, Wade S, Lam KS, Lebl M: Library of libraries: A new approach to synthetic combinatorial design and screening of "pharmacophore" motifs. Proc. Natl. Acad. Sci. USA, 92:5426-5430, 1995.
  372. Lam KS: Synthetic peptide libraries. Molecular Biology and Biotechnology: A Comprehensive Desk Reference. R.A. Meyer ed., pp 880-883 VCH Publisher, 1995.
  373. Lam KS, Lou Q, Zhao ZG, Chen ML, Smith J, Pleshko E, Salmon SE: Idiotype-specific peptides bind to two murine B-cell lymphoma lines, inducing signal transduction. Biomedical Peptides, Proteins and Nucleic Acids 1: 205-210, 1995.
  374. Lam KS, Wu JS, Lou Q: Identification and characterization of a novel peptide substrate specific for src-family tyrosine kinase. Intl J Protein Peptide Res, 45:587-592, 1995.
  375. Lam KS, Wade S, Abdul-Latif F, Lebl M: Application of a dual color detection scheme in the screening of a random combinatorial peptide library. J Immun Methods 180: 219-223, 1995.
  376. Lebl M, Krchnak V, Sepetov NF, Seligmann B, Strop P, Felder S, Lam KS: One-bead-one structure combinatorial libraries. Biopolymers (Peptide Science) 37: 177-198, 1995.
  377. Stankova M, Wade S, Lam KS, Lebl M: Synthesis of combinatorial libraries with only one representation of each structure. Peptide Research 7:292-298, 1994.
  378. Smith MH, Lam KS, Hersh EM, Grimes W: Peptide sequences binding to MHC class I proteins using a synthetic peptide library approach. Molecular Immunology 31: 1431-1437, 1994.
  379. Wu J, Ma QN, Lam KS: Identifying substrate motifs of protein kinases by a random library approach. Biochemistry 33: 14825-14833, 1994.
  380. Stankova M, Issakova O, Sepetov NF, Krchnak V, Lam KS, Lebl M: Application of one-bead-one-structure approach to identification of non-peptide ligands. Drug Development Research 33: 152-156, 1994.
  381. Lam KS, Zhao ZG, Wade S, Krchnak V, Lebl M: Identification of small peptides that interact specifically with a small organic dye. Drug Development Research 33: 157-160, 1994.
  382. Vagner J, Sepetov NF, Krahnak V, Lam KS, Lebl M, Baramy G: Novel methodology for differentiation of "surface" and "interior" areas of polyethylene glycol-polystyrene supports: Application to library screening procedures. In Innovation and Perspectives in Solid Phase Synthesis (R. Epton, Ed.) pp 347-352, Mayflower Worldwide, Birmingham, 1994.
  383. Lebl M, Krchnak V, Sepetov NF, Nikolaev V, Stierandova A, Safar P, Seligmann B, Strop P, Lam KS, Salmon SE: One bead-one structure libraries. In Innovation and Perspectives in Solid Phase Synthesis (R. Epton, Ed.) Vol 3, pp 233-238, Mayflower Worldwide, Birmingham, 1994.
  384. Bartak Z, Bolf J, Kalonsek J, Mudra P, Pavlik M, Pokorny V, Rinnora M, Voburka O, Seniseck K, Krchnak V, Lebl M, Salmon SE, Lam KS: Design and construction of the automatic peptide library synthesizer. Methods: A Companion to Methods in Enzymology 6:432-437, 1994.
  385. Lebl M, Krchnak V, Salmon SE, Lam KS: Screening of completely random one-bead-one-peptide libraries for activities in solution. Methods: A Companion to Methods in Enzymology 6: 381-387, 1994.
  386. Lam KS and Lebl M: Selectide Technology - Bead binding screening. Methods: A companion to Methods in Enzymology 6: 372-380, 1994.
  387. Lam KS and Wu J: Selectide Technology: Substrate motif identification for post-translational modifications. Methods: A Companion to Methods in Enzymology 6: 401-403, 1994.
  388. Lake DF, Lam KS, Peng L, Hersh EM: Molecular cloning, expression and mutagenesis of an anti-insulin single chain Fv (scFv). Molecular Immunology 31: 845-846, 1994.
  389. Lebl M, Krchnak V, Stierandova A, Safar P, Kocis P, Nikolaev V, Sepetov NF, Ferguson R, Seligmann B, Lam KS, Salmon SE: Non-sequenceable and/or nonpeptide libraries. In Peptides: Chemistry, Structure and Biology (Proceedings of the Thirteenth American Peptide Symposium) Hodges R.S. (ed) Escom, Leiden, pp 1007-1008, 1994.
  390. Lebl M, Krchnak V, Sepetov NF, Kocis P, Patek M, Flegelova Z, Ferguson R, Lam KS: Synthetic combinatorial libraries. A new tool for drug design: Methods for identifying the composition of compound from peptide and/or nonpeptide libraries. J Protein Chem 13: 484-486, 1994.
  391. Lam KS, Lebl M, Wade S, Stierandova A, Khattri P, Collin N, Hruby V: Streptavidin-peptide interaction as a model system for molecular recognition. In Peptides: Chemistry, Structure and Biology (Proceedings of the Thirteenth American Peptide Symposium) Hodges R.S. (ed) Escom, Leiden, pp 1005-1006, 1994.
  392. Salmon SE, Lam KS, Lebl M, Kandola A, Khattri P, Healy S, Wade S, Patek M, Kocis P, Krchnak V, Thorpe D, Felder S: An orthogonal partial cleavage approach for solution- phase identification of biologically synthesized peptide libraries. In Peptides: Chemistry, Structure and Biology (Proceedings of the Thirteenth American Peptide Symposium) Hodges R.S. (ed) Escom, Leiden, pp 1001-1002, 1994.
  393. Lam KS, Lebl M, Krchnak V, Lake DF, Smith J, Wade S, Ferguson R, Ackerman-Berrier, Wertman K: Application of Selectide Technology in identifyding (i) a mimotope for a discontinuous epitope, and (ii) D-amino acid ligands. In Peptides: Chemistry, Structure and Biology (Proceedings of the Thirteenth American Peptide Symposium) Hodges R.S. (ed) Escom, Leiden, pp 1003-1004, 1994.
  394. Salmon SE, Lam KS, Felder S, Yeoman H, Schlessinger J, Ullrich A, Krchnak V, Lebl M: One-bead, one chemical compound: Use of the Selectide Process for anticancer drug discovery. Acta Oncologica 33: 127-131, 1994.
  395. Lebl M, Krchnak V, Safar P, Stierandova A, Sepetov NF, Kocis P, Lam KS: Construction and screening of libraries of peptide and non-peptide structures. Techniques in Protein Chemistry, V 541-548, 1994.
  396. Salmon SE, Lam KS, Lebl M, Kandola A, Khattri P, Wade S, Patek M, Kocis P, Krchnak V: An orthogonal partial cleavage approach for solution-phase identification of biologically active peptides from large chemical-synthesized peptide libraries. Proc. Natl. Acad. Sci. USA 90: 11708-11712, 1993.
  397. Lam KS, Lebl M, Krchnak V, Wade S, Abdul-Latif F. Ferguson R, Cuzzocrea C, Wertman K: Discovery of D-amino acid containing ligands with Selectide Technology. Gene 137: 13-16, 1993.
  398. Nikolaiev V, Stierandova A, Krchnak V, Seligmann B, Lam KS, Salmon SE, Lebl M: Peptide-encoding for structure determination of nonsequenceable polymers within libraries synthesized and tested on solid phase supports. Peptide Research 6: 161-170, 1993.
  399. Lam KS: Treatment of B-cell lymphoma using peptides-a novel concept. Western Journal of Medicine 158: 475-479, 1993.
  400. Hruby VJ, Lam KS, Lebl M, Kazmierski W, Hersh EM, Salmon SE: The preparation of large peptide libraries with one peptide per bead, and their use for the discovery of peptides that bind to acceptors. NIDA Research Monograph, 134: 75-83, 1993.
  401. Lam KS, Hruby VJ, Lebl M, Kazmierski WM, Hersh EM, Salmon SE: The chemical synthesis of large random peptide libraries and their use for the discovery of ligands for macromolecular acceptors. Bioorganic and Medicinal Chemistry Letters, 3: 419-424, 1993.
  402. Lebl M, Patek M, Kocis P, Krchnak V, Hruby VJ, Salmon SE, Lam KS: Multiple release of equimolar amounts of linker free peptides from the polymeric carrier. International J of Peptide and Protein Research 41: 201-203, 1993.
  403. Lebl M, Lam KS, Kocis P, et al: Methods for building libraries of peptide structures and determination of consensus sequences. In Peptide 1992 Schneider CH, and Eberie AN (eds), Escom, Leiden, pp 67-69, 1993.
  404. Lam KS and Lebl M: Streptavidin and Avidin Recognize Peptide Ligands with Different Motifs. ImmunoMethods 1: 11-15, 1992.
  405. Lam KS, Alberts DS, Peng YM, Brodar F, Booth A, Matias B, Modiano M, Tuttle R, Lucas VS: Phase I and pharmacokinetics study of BW502U83 (an arylmethyl- aminopropanediol) in cancer patients. Anti-Cancer Drugs 3:219-224, 1992.
  406. Lam KS, Salmon SE, Hersh EM, Hruby V, Kazmierski WM, Knapp RJ: A new type of synthetic peptide library for identifying ligand-binding activity. Nature 354(7):82-84, 1991.
  407. Lam KS, Salmon SE, Hersh EM, Hruby VJ, Al-Obeidi F, Kazmierski WM, Knapp RJ: The Selectide process: Rapid generation of large synthetic peptide libraries linked to identification and structure determination of acceptor-binding ligands. In Peptides: Chemistry, Structure and Biology (Proceedings of the Twelfth American Peptide Symposium), River JE and Smith J (eds), Escom, Leiden, pp 492-495, 1991.
  408. Chong ASF, Pinkard JK, Lam KS, Scuderi P, Hersh EM, Grimes WJ: Ability of cell-sized beads bearing tumor cell membrane proteins to stimulate LAK cells to secrete interferon-gamma and tumor necrosis factor-alpha. Cellular Immunology 134: 96-110, 1991.
  409. Berinstein N, Campbell M, Lam KS, Carswell C, Levy S, Levy R: Idiotype variation in a human B cell line. Journal of Immunology 144: 752-758, 1990.
  410. Lam KS, Scuderi P, Salmon SE: Analysis of the molecular organization of recombinant human tumor necrosis factor (rTNF) in solution using ethylene glycol bis(succinidyl succinate) as the crosslinking reagent. Journal of Biological Response Modifiers 7: 267-275, 1988.
  411. Scuderi P, Sterling KE, Lam KS, Finley PR, Ryan KJ, Ray CG, Peterson E, Slymen DJ, Salmon SE: Raised serum levels of tumor necrosis factor in parasitic infections. The Lancet, Dec 13, 1986, 1364-1365.
  412. Teng NH, Reyes GR, Bieba M, Fry K, Lam KS, Hebert JM: Strategies for stable human monoclonal antibody production; construction of heteromyelomas, in vitro sensitization and molecular cloning of human immunoglobulin genes, in "Human Monoclonal Antibody" (Engleman, E et al eds.) 1985.
  413. Teng NH, Rieva FC, Lam KS, Kaplan HS: Construction and testing of novel mouse-human heteromyelomas for human monoclonal antibody production. Proc Nat Acad Sci USA 80: 7308-7312, 1983.
  414. Teng NH, Rieva FC, Lam KS, Kaplan HS: Construction of heteromyelomas for human monoclonal antibody production, in "Monoclonal Antibodies and Cancer" (B.D. Boss et al, eds) Academic Press, pp 135-142, 1983.
  415. Lam KS and Kasper CB: Comparative studies on the endogenous phosphorylation of microsomal membrane derived from Morris hepatoma, 8-day old rats, and host livers in the absence of added metal ions. Cancer Research 41: 860-863, 1981.
  416. Lam KS and Kasper CB: Chemical synthesis of [32P] pyrophosphate with high specific activity. Analytical Biochem 108: 279-281, 1980.
  417. Lam KS and Kasper CB: Sequence homology analysis of a heterogenous protein population by chemical and enzymic digestion using a two-dimensional sodium dodecyl sulfate polyacrylamide gel system. Analytical Biochem 108: 220-226, 1980.
  418. Lam KS and Kasper CB: Pyrophosphate: protein phosphotransferase: a membrane bound enzyme of the endoplasmic reticulum. Proc Nat Acad Sci USA 77: 1927-1931, 1980.
  419. Lam KS and Kasper CB: Selective endogenous phosphorylation by two liver microsomal polypeptides in the presence of micromolar level of Mg++ ion. J Biol Chem 255:259-266, 1980.
  420. Lam KS and Kasper CB: Electrophoretic analysis of three major nuclear envelope polypeptides: topological relationship and sequence homology. J Biol Chem 254: 11713-11720, 1979.
  421. Lam KS and Kasper CB: Selective phosphorylation of a nuclear envelope polypeptide by an endogenous protein kinase. Biochemistry 18: 307-311, 1979.